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2016
  • Watts, M., Gupta, V., Liddle, C. (2016). Antimicrobials in Cirrhotic Patients After Upper Gastrointestinal Hemorrhage: One Size No Longer Fits All. Clinical Gastroenterology and Hepatology. 14 (2) , 324-325. [More Information]
  • Watts, M., Gupta, V., Liddle, C. (2016). Antimicrobials in cirrhotic patients following upper gastrointestinal hemorrhage: one size no longer fits all. Clinical Gastroenterology and Hepatology. 14 (2) , 324-325. [More Information]
  • Zhou, G., Wilson, G., Hebbard, L., Duan, W., Liddle, C., George, J., Qiao, L. (2016). Aptamers: A promising chemical antibody for cancer therapy. Oncotarget. 7 (12) , 13446-13463. [More Information]

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  • Zhao, X., Hirota, T., Han, X., Cho, H., Chong, L., Lamia, K., Liu, S., Atkins, A., Banayo, E., Liddle, C., et al (2016). Circadian Amplitude Regulation via FBXW7-Targeted REV-ERBalpha Degradation. Cell. 165 (7) , 1644-1657. [More Information]
  • Booth, D., Ding, N., Parnell, G., Shahijanian, F., Coulter, S., Schibeci, S., Atkins, A., Stewart, G., Evans, R., Downes, M., Liddle, C. (2016). Cistromic and genetic evidence that the vitamin D receptor mediates susceptibility to latitude-dependent autoimmune diseases. Genes and Immunity. 17 (4) , 213-219. [More Information]
  • Eslam, M., Mangia, A., Berg, T., Chan, H., Irving, W., Dore, G., Abate, M., Bugianesi, E., Adams, L., Najim, M., Weltman, M., Rahme, A., Booth, D., Liddle, C., Douglas, M., van der Poorten, D., George, J., White, R., Leung, R., et al (2016). Diverse impacts of the rs58542926 E167K variant in TM6SF2 on viral and metabolic liver disease phenotypes. Hepatology. 64 (1) , 34-46. [More Information]
  • Fox, P., Balleine, R., Lee, C., Gao, B., Balakrishnar, B., Menzies, A., Yeap, S., Ali, S., Gebski, V., Provan, P., Liddle, C., Hui, R., Kefford, R., Wong, K., Wilcken, N., Gurney, H., et al (2016). Dose escalation of tamoxifen in patients with low endoxifen level: Evidence for therapeutic drug monitoring - The TADE study. Clinical Cancer Research. 22 (13) , 3164-3171. [More Information]
  • Yoshihara, E., Wei, Z., Lin, C., Fang, S., Ahmadian, M., Kida, Y., Tseng, T., Dai, Y., Yu, R., Liddle, C., et al (2016). ERRY Is Required for the Metabolic Maturation of Therapeutically Functional Glucose-Responsive � Cells. Cell Metabolism. 23 (4) , 622-634. [More Information]
  • Eslam, M., Hashem, A., Romero-Gomez, M., Berg, T., Dore, G., Mangia, A., Chan, H., Irving, W., Sheridan, D., Abate, M., Weltman, M., Kelaeng, K., Ahlenstiel, G., Liddle, C., Douglas, M., Booth, D., George, J., et al (2016). FibroGENE: A gene-based model for staging liver fibrosis. Journal of Hepatology. 64 (2) , 390-398. [More Information]
  • O'Connor, K., Read, S., Wang, M., Schibeci, S., Eslam, M., Ong, A., Weltman, M., Douglas, M., Mazzola, A., Craxi, A., Stewart, G., Liddle, C., George, J., Ahlenstiel, G., Booth, D., et al (2016). IFNL3/4 genotype is associated with altered immune cell populations in peripheral blood in chronic hepatitis C infection. Genes and Immunity. 17 (6) , 328-334. [More Information]
  • Thabet, K., Asimakopoulos, A., Shojaei, M., Romero-Gomez, M., Mangia, A., Irving, W., Berg, T., Dore, G., Gronbaek, H., Sheridan, D., White, R., Douglas, M., Liddle, C., van der Poorten, D., George, J., Eslam, M., et al (2016). MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C. Nature Communications. 7 , 1-8. [More Information]
  • Bullock, M., Lim, G., Li, C., Choi, I., Kochhar, S., Liddle, C., Zhang, L., Clifton-Bligh, R. (2016). Thyroid transcription factor FOXE1 interacts with ETS factor ELK1 to co-regulate TERT. Oncotarget. 7 (52) , 85948-85962.
  • Bullock, M., Lim, G., Li, C., Choi, I., Kochhar, S., Liddle, C., Zhang, L., Clifton-Bligh, R. (2016). Thyroid transcription factor foxe1 interacts with ets factor elk1 to co-regulate tert. Oncotarget. 7 (52) , 85948-85962.

2015
  • Reilly, S., Ahmadian, M., Zamarron, B., Chang, L., Uhm, M., Poirier, B., Peng, X., Krause, D., Korytnaya, E., Neidert, A., Liddle, C., et al (2015). A subcutaneous adipose tissue-liver signalling axis controls hepatic gluconeogenesis. Nature Communications. 6 , 1-12. [More Information]
  • Ding, N., Hah, N., Yu, R., Sherman, M., Benner, C., Leblanc, M., He, M., Liddle, C., Downes, M., Evans, R. (2015). BRD4 is a novel therapeutic target for liver fibrosis. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 112 (51) , 15713-15718. [More Information]
  • Arensman, M., Nguyen, P., Kershaw, K., Lay, A., Ostertag-Hill, C., Sherman, M., Downes, M., Liddle, C., Evans, R., Dawson, D. (2015). Calcipotriol Targets LRP6 to Inhibit Wnt Signaling in Pancreatic Cancer. Molecular Cancer Research. 13 (11) , 1509-1519. [More Information]

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  • Hallwirth, C., Garg, G., Peters, T., Kramer, B., Malani, N., Hyman, J., Ruan, X., Ginn, S., Hetherington, N., Veeravalli, L., Liddle, C., Alexander, I., et al (2015). Coherence analysis discriminates between retroviral integration patterns in CD34(+) cells transduced under differing clinical trial conditions. Molecular Therapy - Methods & Clinical Development. 2 , 1-10. [More Information]
  • Pei, L., Mu, Y., Leblanc, M., Alaynick, W., Barish, G., Pankratz, M., Tseng, T., Kaufman, S., Liddle, C., Yu, R., et al (2015). Dependence of Hippocampal Function on ERR-Gamma-Regulated Mitochondrial Metabolism. Cell Metabolism. 21 (4) , 628-636. [More Information]
  • Bapat, S., Suh, J., Fang, S., Liu, S., Zhang, Y., Cheng, A., Zhou, C., Liang, Y., Leblanc, M., Liddle, C., et al (2015). Depletion of fat-resident Treg cells prevents age-associated insulin resistance. Nature. 528 (7580) , 137-141. [More Information]
  • Kida, Y., Kawamura, T., Wei, Z., Sogo, T., Jacinto, S., Shigeno, A., Kushige, H., Yoshihara, E., Liddle, C., Ecker, J., et al (2015). ERRs Mediate a Metabolic Switch Required for Somatic Cell Reprogramming to Pluripotency. Cell Stem Cell. 16 (5) , 547-555. [More Information]
  • Scott, C., Cha, K., Rao, R., Liddle, C., George, J., Gunton, J. (2015). Hepatocyte- Specific Deletion of ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator) Results in Altered Fibrotic Gene Expression in the Thioacetamide Model of Liver Injury. PloS One. 10 (3) , 1-11. [More Information]
  • Wall, C., Whyte, J., Suh, J., Fan, W., Collins, B., Liddle, C., Yu, R., Atkins, A., Naviaux, J., Li, K., et al (2015). High-fat diet and FGF21 cooperatively promote aerobic thermogenesis in mtDNA mutator mice. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 112 (28) , 8714-8719. [More Information]
  • Eslam, M., Hashem, A., Leung, R., Romero-Gomez, M., Berg, T., Dore, G., Chan, H., Irving, W., Sheridan, D., Abate, M., Weltman, M., Douglas, M., Liddle, C., Booth, D., George, J., Ahlenstiel, G., et al (2015). Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease. Nature Communications. 6 , 1-10. [More Information]
  • Fang, S., Suh, J., Reilly, S., Yu, E., Osborn, O., Lackey, D., Yoshihara, E., Perino, A., Jacinto, S., Lukasheva, Y., Coulter, S., Liddle, C., et al (2015). Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance. Nature Medicine. 21 (2) , 159-165. [More Information]
  • Liddle, C., Goodwin, B. (2015). Xenobiotic Related Induction of Gene Expression (United States).

2014
  • Zhuang, L., Hulin, J., Gromova, A., Nguyen, T., Yu, R., Liddle, C., Downes, M., Evans, R., Makarenkova, H., Meech, R. (2014). Barx2 and Pax7 Have Antagonistic Functions in Regulation of Wnt Signaling and Satellite Cell Differentiation. Stem Cells. 32 (6) , 1661-1673. [More Information]
  • Khushi, M., Liddle, C., Clarke, C., Graham, J. (2014). Binding Sites Analyser (BiSA): Software for Genomic Binding Sites Archiving and Overlap Analysis. PloS One. 9 (2) , 1-12. [More Information]
  • Suh, J., Jonker, J., Ahmadian, M., Goetz, R., Lackey, D., Osborn, O., Huang, Z., Liu, W., Yoshihara, E., van Dijk, T., Liddle, C., et al (2014). Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer. Nature. 513 (7518) , 436-439. [More Information]

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  • O'Connor, K., Parnell, G., Patrick, E., Ahlenstiel, G., Suppiah, V., van der Poorten, D., Read, S., Leung, R., Douglas, M., Yang, J., Stewart, G., Liddle, C., George, J., Booth, D. (2014). Hepatic metallothionein expression in chronic hepatitis C virus infection is IFNL3 genotype-dependent. Genes and Immunity. 15 (2) , 88-94. [More Information]
  • O'Connor, K., Ahlenstiel, G., Suppiah, V., Schibeci, S., Ong, A., Leung, R., van der Poorten, D., Douglas, M., Weltman, M., Stewart, G., Liddle, C., George, J., Booth, D. (2014). IFNL3 mediates interaction between innate immune cells: Implications for hepatitis C virus pathogenesis. Innate Immunity. 20 (6) , 598-605. [More Information]
  • Vanwijngaerden, Y., Langouche, L., Derde, S., Liddle, C., Coulter, S., van den Berghe, G., Mesotten, D. (2014). Impact of Parenteral Nutrition Versus Fasting on Hepatic Bile Acid Production and Transport in a Rabbit Model of Prolonged Critical Illness. Shock. 41 (1) , 48-54. [More Information]
  • Lu, B., Bridges, D., Yang, Y., Fisher, K., Cheng, A., Chang, L., Meng, Z., Lin, J., Downes, M., Yu, R., Liddle, C., et al (2014). Metabolic Crosstalk: molecular links between glycogen and lipid metabolism in obesity. Diabetes. 63 (9) , 2935-2948. [More Information]
  • Parnell, G., Gatt, P., McKay, F., Schibeci, S., Krupa, M., Powell, J., Visscher, P., Montgomery, G., Lechner-Scott, J., Broadley, S., Liddle, C., Vucic, S., Stewart, G., Booth, D., et al (2014). Ribosomal protein S6 mRNA is a biomarker upregulated in multiple sclerosis, downregulated by interferon treatment, and affected by season. Multiple Sclerosis Journal. 20 (6) , 675-685. [More Information]
  • Shahijanian, F., Parnell, G., McKay, F., Gatt, P., Shojaei, M., O'Connor, K., Schibeci, S., Brilot-Turville, F., Liddle, C., Batten, M., Stewart, G., Booth, D. (2014). The CYP27B1 variant associated with increased risk of autoimmune disease is underexpressed in tolerising dendritic cells. Human Molecular Genetics. 23 (6) , 1425-1434. [More Information]
  • Liddle, C., Goodwin, B., Robertson, G. (2014). Transgenic Animals For Analysing CYP3A4 Cytochrome P450 Gene Regulation (Japan).
  • Sherman, M., Yu, R., Engle, D., Ding, N., Atkins, A., Tiriac, H., Collisson, E., Connor, F., Van Dyke, T., Kozlov, S., Lau, S., Gunton, J., Liddle, C., et al (2014). Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy. Cell. 159 (1) , 80-93. [More Information]
  • Vanwijngaerden, Y., Langouche, L., Brunner, R., Debaveye, Y., Gielen, M., Casaer, M., Liddle, C., Coulter, S., Wouters, P., Wilmer, A., et al (2014). Withholding Parenteral Nutrition During Critical Illness Increases Plasma Bilirubin but Lowers the Incidence of Biliary Sludge. Hepatology. 60 (1) , 202-210. [More Information]

2013
  • Ding, N., Yu, R., Subramaniam, N., Sherman, M., Wilson, C., Rao, R., Leblanc, M., Coulter, S., He, M., Scott, C., Liddle, C., et al (2013). A Vitamin D Receptor/SMAD Genomic Circuit Gates Hepatic Fibrotic Response. Cell. 153 (3) , 601-613. [More Information]
  • Reilly, S., Chiang, S., Decker, S., Chang, L., Uhm, M., Larsen, M., Rubin, J., Mowers, J., White, N., Hochberg, I., Liddle, C., et al (2013). An inhibitor of the protein kinases TBK1 and IKK-{epsilon} improves obesity-related metabolic dysfunctions in mice. Nature Medicine. 19 (3) , 313-321. [More Information]
  • Kacevska, M., Mahns, A., Sharma, R., Clarke, S., Robertson, G., Liddle, C. (2013). Extra-Hepatic Cancer Represses Hepatic Drug Metabolism Via Interleukin (IL)-6 Signalling. Pharmaceutical Research. 30 (9) , 2270-2278. [More Information]

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  • Ding, N., Liddle, C., Evans, R., Downes, M. (2013). Hepatic actions of vitamin D receptor ligands: a sunshine option for chronic liver disease?. Expert Review of Clinical Pharmacology. 6 (6) , 597-599. [More Information]
  • van der Poorten, D., Samer, C., Ramezani-Moghadam, M., Coulter, S., Kacevska, M., Schrijnders, D., Wu, L., McLeod, D., Bugianesi, E., Komuta, M., Liddle, C., Hebbard, L., George, J., et al (2013). Hepatic Fat Loss in Advanced Nonalcoholic Steatohepatitis: Are Alterations in Serum Adiponectin the Cause?. Hepatology. 57 (6) , 2180-2188. [More Information]
  • Uhlenhaut, N., Barish, G., Yu, R., Downes, M., Karunasiri, M., Liddle, C., Schwalie, P., Hubner, N., Evans, R. (2013). Insights into Negative Regulation by the Glucocorticoid Receptor from Genome-wide Profiling of Inflammatory Cistromes. Molecular Cell. 49 (1) , 158-171. [More Information]
  • Ahmadian, M., Suh, J., Hah, N., Liddle, C., Atkins, A., Downes, M., Evans, R. (2013). PPARγ signaling and metabolism: the good, the bad and the future. Nature Medicine. 19 (5) , 557-566. [More Information]
  • O'Connor, K., Liddle, C. (2013). Prospective data collection of off-label use of rituximab in Australian public hospitals. Internal Medicine Journal. 43 (8) , 863-870. [More Information]
  • Liddle, C., Goodwin, B. (2013). Xenobiotic Related Induction of Gene Expression of Cytochrome CYP3A4 (Switzerland).

2012
  • Jonker, J., Liddle, C., Downes, M. (2012). FXR and PXR: Potential therapeutic targets in cholestasis. Journal of Steroid Biochemistry and Molecular Biology. 130 (3-5) , 147-158. [More Information]
  • Subramaniam, N., Sherman, M., Rao, R., Wilson, C., Coulter, S., Atkins, A., Evans, R., Liddle, C., Downes, M. (2012). Metformin-mediated Bambi expression in hepatic stellate cells induces prosurvival Wnt/β-catenin signaling. Cancer Prevention Research. 5 (4) , 553-561. [More Information]
  • Cho, H., Zhao, X., Hatori, M., Yu, R., Barish, G., Lam, M., Chong, L., DiTacchio, L., Atkins, A., Glass, C., Liddle, C., et al (2012). Regulation of circadian behaviour and metabolism by REV-ERB-a and REV-ERB-B. Nature. 485 (7396) , 123-127. [More Information]

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  • Liddle, C., Goodwin, B., Robertson, G. (2012). Transgenic Animals For Analysing CYP3A4 Cytochrome P450 Gene Regulation (USA).

2011
  • Vanwijngaerden, Y., Wauters, J., Langouche, L., Perre, S., Liddle, C., Coulter, S., Vanderborght, S., Roskams, T., Wilmer, A., et al, V. (2011). Critical illness evokes elevated circulating bile acids related to altered hepatic transporter and nuclear receptor expression. Hepatology. 54 (5) , 1741-1752. [More Information]
  • Kacevska, M., Downes, M., Sharma, R., Evans, R., Clarke, S., Liddle, C., Robertson, G. (2011). Extrahepatic Cancer Suppresses Nuclear Receptor-Regulated Drug Metabolism. Clinical Cancer Research. 17 (10) , 3170-3180. [More Information]
  • Wu, A., Coulter, S., Liddle, C., Wong, A., Eastham-Anderson, J., French, D., Peterson, A., Sonoda, J. (2011). FGF19 Regulates Cell Proliferation, Glucose and Bile Acid Metabolism via FGFR4-Dependent and Independent Pathways. PloS One. 6 (3) , 1-11. [More Information]

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  • Chmiel, K., Suan, D., Liddle, C., Nankivell (Nankievell), B., Ibrahim, R., Bautista, C., Thompson, J., Fulcher, D., Kefford, R. (2011). Resolution of Severe Ipilimumab-Induced Hepatitis After Antithymocyte Globulin Therapy. Journal of Clinical Oncology. 29 (9) , 237-240. [More Information]
  • Suan, D., O'Connor, K., Booth, D., Liddle, C., Stewart, G. (2011). Voriconazole toxicity related to polymorphisms in CYP2C19. Internal Medicine Journal. 41 (4) , 364-365. [More Information]

2010
  • Liddle, C., Stedman, C., Downes, M. (2010). Signaling Pathways in Liver Diseases: PXR and CAR. Signaling Pathways in Liver Diseases. , 333-344.
  • Goodwin, B., Liddle, C. (2010). Xenobiotic Related Induction of Gene Expression (Japan).

2009
  • Hilmer, S., Seale, J., Le Couteur, D., Crampton, R., Liddle, C. (2009). Do medical courses adequately prepare interns for safe and effective prescribing in New South Wales public hospitals?. Internal Medicine Journal. 39 (7) , 428-434. [More Information]
  • Jonker, J., Stedman, C., Liddle, C., Downes, M. (2009). Hepatobiliary ABC transporters: physiology, regulation and implications for disease. Frontiers in Bioscience. 14 , 4904-4920. [More Information]
  • Liddle, C., Goodwin, B., Robertson, G. (2009). Transgenic Animals For Analysing CYP3A4 Cytochrome P450 Gene Regulation (USA).

2008
  • Sharma, R., Kacevska, M., London, R., Clarke, S., Liddle, C., Robertson, G. (2008). Downregulation of drug transport and metabolism in mice bearing extra-hepatic malignancies. British Journal of Cancer. 98 (1) , 91-97. [More Information]
  • Robertson, G., Liddle, C., Clarke, S. (2008). Inflammation and Altered Drug Clearance in Cancer: Transcriptional Repression of a Human CYP3A4 Transgene in Tumor-bearing Mice. Pharmacology and Therapeutics. 83 (6) , 894-897. [More Information]
  • Kacevska, M., Robertson, G., Clarke, S., Liddle, C. (2008). Inflammation and CYP3A4-mediated drug metabolism in advanced cancer: impact and implications for chemotherapeutic drug dosing. Expert Opinion on Drug Metabolism and Toxicology. 4 (2) , 137-149. [More Information]

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  • Downes, M., Liddle, C. (2008). Look who's talking: nuclear receptors in the liver and gastrointestinal tract.. Cell Metabolism. 7 (3) , 195-199. [More Information]
  • Liddle, C. (2008). Mass in the Liver. Gastroenterology and Hepatology: a clinical handbook. 1 , 461-467.
  • George, J., Liddle, C. (2008). Nonalcoholic fatty liver disease: Pathogenesis and potential for nuclear receptors as therapeutic targets. Molecular Pharmaceutics. 5 (1) , 49-59. [More Information]
  • Morgan, E., Goralski, K., Piquette-Miller, M., Renton, K., Robertson, G., Chaluvadi, M., Charles, K., Clarke, S., Kacevska, M., Liddle, C., et al (2008). Regulation of drug-metabolizing enzymes and transporters in infection, inflammation, and cancer. Drug Metabolism and Disposition. 36 (2) , 205-216. [More Information]
  • Sharma, R., Zucknick, M., London, R., Kacevska, M., Liddle, C., Clarke, S. (2008). Systemic inflammatory response predicts prognosis in patients with advanced-stage colorectal cancer. Clinical Colorectal Cancer. 7 (5) , 331-337. [More Information]
  • Sharma, R., Hoskins, J., Rivory, L., Zucknick, M., London, R., Liddle, C., Clarke, S. (2008). Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms and toxicity to capecitabine in advanced colorectal cancer patients. Clinical Cancer Research. 14 (3) , 817-825. [More Information]
  • Klumpen, H., Liddle, C., Gurney, H. (2008). Transporter pumps and imatinib: A cause of pharmacokinetic resistance?. Cancer Biology & Therapy. 7 (3) , 416-418.

2007
  • Sharma, R., Koller, L., Barclay, P., Liddle, C. (2007). Evaluation of the off-label usage of rituximab in a large teaching hospital in New South Wales.. Internal Medicine Journal. 37 (8) , 569-571. [More Information]
  • Liddle, C., Stedman, C. (2007). Hepatic Metabolism of Drugs. The Textbook of Hepatology: From Basic Science to Clinical Practice. , 241-249.

2006
  • Stedman, C., Liddle, C., Coulter, S., Sonoda, J., Alvarez, J., Evans, R., Downes, M. (2006). Benefit of farnesoid X receptor inhibition in obstructive cholestasis.. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 103 (30) , 11323-11328.
  • Liddle, C., Goodwin, B. (2006). Cytochrome P450 Transcriptional Enhancer Nucleic Acid Molecule (USA).
  • Charles (nee Slaviero), K., Rivory, L., Brown, S., Liddle, C., Clarke, S., Robertson, G. (2006). Transcriptional repression of hepatic cytochrome P450 3A4 gene in the presence of cancer. Clinical Cancer Research. 12 (24) , 7492-7497. [More Information]

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  • Liddle, C., Goodwin, B. (2006). Xenobiotic Related Induction Of Gene Expression (USA).

2005
  • Stedman, C., Liddle, C., Coulter, S., Sonoda, J., Alvarez, J., Moore, D., Evans, R., Downes, M. (2005). Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury.. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 102 (6) , 2063-2068.
  • Sonoda, J., Chong, L., Downes, M., Barish, G., Coulter, S., Liddle, C., Lee, C., Evans, R. (2005). Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites.. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 102 (6) , 2198-203.
  • Esteban, L., Fong, C., Amr, D., Cock, T., Allison, S., Flanagan, J., Liddle, C., Eisman, J., Gardiner, E. (2005). Promoter-, cell-, and ligand-specific transactivation responses of the VDRB1 isoform.. Biochemical and Biophysical Research Communications. 334 (1) , 9-15.

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  • Liddle, C., Rangan, G., Coombes, J., Mreich, E. (2005). Rapamycin worsens renal function and intratubular cast formation in protein overload nephropathy.. Kidney International.

2004
  • Wong, M., Balleine, R., Collins, M., Liddle, C., Clarke, C., Gurney, H. (2004). Cyp3A5 Genotype And Midazolam Clearance In Australian Patients Receiving Chemotherapy. Pharmacology and Therapeutics. 75 (6) , 529-538. [More Information]
  • Coverdale, S., Khan, M., Byth Wilson, K., Lin, R., Weltman, M., George, J., Samarasinghe, D., Liddle, C., Farrell, G., Kench, J., Crewe, E. (2004). Effects Of Interferon Treatment Response On Liver Complications Of Chronic Hepatitis C: 9-Year Follow-Up Study.. American Journal of Gastroenterology. 99 (4) , 636-644.
  • Stedman, C., Robertson, G., Coulter, S., Liddle, C. (2004). Feed-Forward Regulation Of Bile Acid Detoxification By Cyp3A4: Studies In Humanized Transgenic Mice. Journal of Biological Chemistry. 279 (12) , 11336-11346.

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  • Sud, A., Hui, J., Farrell, G., Bandara, P., Kench, J., Fung, C., Lin, R., Samarasinghe, D., Liddle, C., McCaughan, G., George, J. (2004). Improved Prediction Of Fibrosis In Chronic Hepatitis C Using Measures Of Insulin Resistance In A Probability Index.. Hepatology. 39 (5) , 1239-1247. [More Information]

2003
  • Coverdale, S., Samarasinghe, D., Lin, R., Kench, J., Byth Wilson, K., Khan, M., Crewe, E., Liddle, C., George, J., Farrell, G. (2003). Changes in Antipyrine Clearance and Platelet Count, but Not Conventional Liver Tests, Correlate With Fibrotic Change in Chronic Hepatitis C: Value for Predicting Fibrotic Progression. American Journal of Gastroenterology. 98 (6) , 1384-1390.
  • Kumar, D., Wallington-Beddoe, C., George, J., Lin, R., Samarasinghe, D., Liddle, C., Farrell, G. (2003). Effectiveness of interferon alfa-2b/ribavirin combination therapy for chronic hapatitis c in a clinic setting. Medical Journal of Australia. 178 (6) , 267-271.
  • Mesotten, D., Van den Berghe, G., Liddle, C., Coulter, S., McDougall, F., Baxter, R., Delhanty, P. (2003). Growth hormone modulation of the rat hepatic bile transporter system in endotoxin-induced cholestasis. Endocrinology. 144 (9) , 4008-4017.

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  • Liddle, C., Robertson, G. (2003). Predicting inductive drug-drug interactions. Pharmacogenomics. 4 (2) , 141-152.
  • Robertson, G., Field, J., Goodwin, B., Bierach, S., Tran, M., Lehnert, A., Liddle, C. (2003). Transgenic mouse models of human CYP3A4 gene regulation. Molecular Pharmacology. 64 (1) , 42-50.

2002
  • Hui, J., George, J., Liddle, C., Lin, R., Samarasinghe, D., Crewe, E., Farrell, G. (2002). Changes in Serum Albumin During Treatment of Chronic Hepatitis B With Lamivudine: Effects of Response and Emergence of Drug Resistance. American Journal of Gastroenterology. 97 (4) , 1003-1009.
  • Farrell, G., Liddle, C. (2002). Drugs and the liver updated, 2002. Seminars in Liver Disease. 22 (2) , 109-113.
  • Hui, J., Kench, J., Farrell, G., Lin, R., Samarasinghe, D., Liddle, C., Byth, K., George, J. (2002). Genotype-specific mechanisms for hepatic steatosis in chronic hepatitis C infection. Journal of Gastroenterology and Hepatology. 17 (8) , 873-881.

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  • Hui, J., Farrell, G., Lin, R., Samarasinghe, D., Liddle, C., George, J., Kench, J., Byth, K. (2002). Hepatic Steatosis in Chronic Hepatitis C Infection. Journal of Gastroenterology and Hepatology. 17 (8) , 873-881.
  • Chitturi, S., Weltman, M., Farrell, G., McDonald, D., Liddle, C., Samarasinghe, D., Lin, R., Abeygunasekera, S., George, J. (2002). HFE Mutations, Hepatic Iron, and Fibrosis: Ethnic-Specification Association of NASH with C282Y but not with Fibrotic Severity. Hepatology. 36 (1) , 142-149.
  • Chitturi, S., Abeygunasekera, S., Farrell, G., Holmes-Walker, J., Hui, J., Fung, C., Karim, R., Lin, R., Samarasinghe, D., Liddle, C., Weltman, M., George, J. (2002). NASH and Insulin Resistance: Insulin Hypersecretion and Specific Association with the Insulin Resistance Syndrome. Hepatology. 35 (2) , 373-379.
  • Liddle, C., Goodwin, B. (2002). Regulation of hepatic drug metabolism: role of the nuclear receptors PXR and CAR. Seminars in Liver Disease. 22 (2) , 115-122.
  • Chitturi, S., Farrell, G., Frost, L., Kriketos, A., Lin, R., Liddle, C., Samarasinghe, D., George, J. (2002). Serum Leptin in NASH Correlates with Hepatic Steatosis but not Fibrosis: A Manifestation of Lipotoxicity?. Hepatology. 36 (2) , 403-409.
  • Spurdle, A., Goodwin, B., Hodgson, E., Liddle, C., Hopper, J., Chen, X., Purdie, D., McCredie, M., Giles, G., Chenevix-Trench, G. (2002). The CYP3A4*1B polymorphism has no functional significance and is not associated with risk of breast or ovarian cancer. Pharmacogenetics and Genomics. 12 (5) , 355-366.
  • Goodwin, B., Hodgson, E., D'Costa, D., Robertson, G., Liddle, C. (2002). Transcriptional regulation of the human CYP3A4 gene by the constitutive androstane receptor. Molecular Pharmacology. 62 , 359-365.

2001
  • Amr, D., Liddle, C. (2001). A novel polymorphism affects transcription of the CYP3A4 gene. Journal of Gastroenterology and Hepatology. 16
  • Stedman, C., Robertson, G., Liddle, C., Field, J. (2001). Hepatoprotective response to cholestasis: bile duct ligation activates transcription of a human activates transcription of a human CYP3A4/LACZ transgene in mice. Journal of Gastroenterology and Hepatology. 16
  • Coverdale, S., Samarasinghe, D., Lin, R., Liddle, C., George, J., Farrell, G., Kench, J., Byth, K., Khan, M., Crewe, E. (2001). Prediction of histological progression in chronic hepatitis C. Asia Pacific Digestive Week 2001. 16

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  • Farrell, G., Liddle, C., Samarasinghe, D., Chitturi, S., Frost, L. (2001). Serum leptin is a predictor of severity of hepatic steatosis in NASH but does not correlate with fibrotic severity. Journal of Gastroenterology and Hepatology. 16
  • Farrell, G., Liddle, C., Samarasinghe, D., Lin, R., George, J., Chitturi, S., Frost, L. (2001). Serum Leptin: An independent predictor of hepatic steatosis but not fibrotic severity in nonalcoholic steatohepatitis. Hepatology. 34 , 752-752.