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Publications

Professor Jon IredellDirector, Centre for Infectious Disease and Microbiology; Professor of Medicine and Microbiology (conj.), Sydney Medical School; Senior Staff Specialist, Infectious Diseases & Microbiology; Westmead Hospital/ ICPMR; Senior Practitioner Fellow, NHMRC - Critical Infection / BARRD Group
8627 3411

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Critical Infection / BARRD Group, Infection and Immunity

Publications

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2016
  • Agyekum, A., Fajardo-Lubián, A., Ansong, D., Partridge, S., Agbenyega, T., Iredell, J. (2016). blaCTX-M-15 carried by IncF-type plasmids is the dominant ESBL gene in Escherichia coli and Klebsiella pneumoniae at a hospital in Ghana. Diagnostic Microbiology and Infectious Disease. 84 (4) , 328-333. [More Information]
  • Agyekum, A., Fajardo-Lubián, A., Ai, X., Ginn, A., Zong, Z., Guo, X., Turnidge, J., Partridge, S., Iredell, J. (2016). Predictability of Phenotype in Relation to Common �-Lactam Resistance Mechanisms in Escherichia coli and Klebsiella pneumoniae. Journal of Clinical Microbiology. 54 (5) , 1243-1250. [More Information]
  • Playford, E., Lipman, J., Jones, M., Lau, A., Kabir, M., Chen, S., Marriott, D., Seppelt, I., Gottlieb, T., Cheung, W., Iredell, J., Sorrell, T., et al (2016). Problematic dichotomisation of risk for ICU-acquired invasive candidiasis: results using a risk predictive model to categorise three levels of risk from a multicentre prospective cohort of Australian ICU patients. Clinical Infectious Diseases. 63 (11) , 1463-1469. [More Information]
2015
  • Lau, A., Kabir, M., Chen, S., Playford, E., Marriott, D., Jones, M., Lipman, J., McBryde, E., Gottlieb, T., Cheung, W., Seppelt, I., Iredell, J., Sorrell, T. (2015). Candida colonization as a risk marker for invasive candidiasis in mixed medical-surgical intensive care units: development and evaluation of a simple, standard protocol. Journal of Clinical Microbiology. 53 (4) , 1324-1330. [More Information]
  • Zong, Z., Ginn, A., Dobiasova, H., Iredell, J., Partridge, S. (2015). Different IncI1 plasmids from Escherichia coli carry ISEcp1-blaCTX-M-15 associated with different Tn2-derived elements. Plasmid. 80 , 118-126. [More Information]
  • Tagg, K., Ginn, A., Jiang, X., Ellem, J., Partridge, S., Iredell, J. (2015). Distribution of acquired AmpC Beta-lactamase genes in Sydney, Australia. Diagnostic Microbiology and Infectious Disease. 83 (1) , 56-58. [More Information]

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  • Partridge, S., Ginn, A., Wiklendt, A., Ellem, J., Wong, J., Ingram, P., Guy, S., Garner, S., Iredell, J. (2015). Emergence of blaKPC carbapenemase genes in Australia. International Journal of Antimicrobial Agents. 45 (2) , 130-136. [More Information]
  • Kok, J., Ng, J., Li, S. C., Giannoutsos, J., Nayyar, V., Iredell, J. R., Dwyer, D. E. and Chen, S. C. A. (2015). Evaluation of point-of-care testing in critically unwell patients: comparison with clinical laboratory analysers and applicability to patients with Ebolavirus infection. Pathology. 5 (47) , 405-9.
  • Brouwer, M., Tagg, K., Mevius, D., Iredell, J., Bossers, A., Smith, H., Partridge, S. (2015). IncI shufflons: Assembly issues in the next-generation sequencing era. Plasmid. 80 , 111-117. [More Information]
  • Tagg, K., Ginn, A., Partridge, S., Iredell, J. (2015). MALDI-TOF Mass Spectrometry for Multilocus Sequence Typing of Escherichia coli Reveals Diversity among Isolates Carrying blaCMY-2-Like Genes. PloS One. 10 (11) , 1-10. [More Information]
  • Harris, P. N. A., Peleg, A. Y., Iredell, J., Ingram, P. R., Miyakis, S., Stewardson, A. J., Rogers, B. A., McBryde, E. S., Roberts, J. A., Lipman, J., Athan, E., Paul, S. K., Baker, P., Harris-Brown, T. and Paterson, D. L. (2015). Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections due to ceftriaxone non-susceptible Escherichia coli and Klebsiella spp (the MERINO trial): study protocol for a randomised controlled trial. Trials. (16)
  • Keighley, C., Hamor, P., Chen, S., Watts, M., Douglas, M., Kok, J., O'Sullivan, M., Mitchell, D., Packham, D., Sorrell, T., Iredell, J. (2015). Modern technology and infectious diseases activity data: how can we use this for service planning?. Internal Medicine Journal. 45 (6) , 688-688. [More Information]
  • Zhou, F., O'Sullivan, M., Iredell, J., Sintchenko, V., Gilbert, G., Dwyer, D. (2015). Molecular analysis of Enterovirus C species using the 5' untranslated region and VP1 region. Journal of Human Virology & Retrovirology. 2 (2) , 1-12. [More Information]
  • Sloots, T. P., Nissen, M. D., Ginn, A. N. and Iredell, J. R. (2015). Rapid identification of pathogens using molecular techniques. Pathology. 3 (47) , 191-198.
  • Kamruzzaman, M., Patterson, J., Shoma, S., Ginn, A., Partridge, S., Iredell, J. (2015). Relative strengths of promoters provided by common mobile genetic elements associated with resistance gene expression in Gram-negative bacteria. Antimicrobial Agents and Chemotherapy. 59 (8) , 5088-5091. [More Information]
2014
  • Watts, M. R., James, G., Sultana, Y., Ginn, A. N., Outhred, A. C., Kong, F., Verweij, J. J., Iredell, J. R., Chen, S. C. A. and Lee, R. (2014). A Loop-Mediated Isothermal Amplification (LAMP) Assay for Strongyloides stercoralis in Stool That Uses a Visual Detection Method with SYTO-82 Fluorescent Dye. American Journal of Tropical Medicine and Hygiene. 2 (90) , 306-311.
  • Shoma, S., Kamruzzaman, M., Ginn, A., Iredell, J., Partridge, S. (2014). Characterization of multidrug-resistant Klebsiella pneumoniae from Australia carrying blaNDM-1. Diagnostic microbiology and infectious disease. 78 (1) , 93-97. [More Information]
  • Tagg, K., Iredell, J., Partridge, S. (2014). Complete Sequencing of IncI1 Sequence Type 2 Plasmid pJIE512b Indicates Mobilization of blaCMY-2 from an IncA/C Plasmid. Antimicrobial Agents and Chemotherapy. 58 (8) , 4949-4952. [More Information]

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  • Knox, J., Jadhav, S., Sevior, D., Agyekum, A., Whipp, M., Waring, L., Iredell, J. and Palombo, E. (2014). Phenotypic Detection of Carbapenemase-Producing Enterobacteriaceae by Use of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry and the Carba NP Test. Journal of Clinical Microbiology. 7 (82) , 3058-3065.
  • Ginn, A., Wiklendt, A., Zong, Z., Lin, R., Teo, J., Tambyah, P., Peterson, L., Kaul, K., Partridge, S., Iredell, J. (2014). Prediction of major antibiotic resistance in Escherichia coli and Klebsiella pneumoniae in Singapore, USA and China using a limited set of gene targets. International Journal of Antimicrobial Agents. 43 (6) , 563-565. [More Information]
  • Hazelton, B., Thomas, L. C., Olma, T., Kok, J., O'Sullivan, M., Chen, S. C. A. and Iredell, J. R. (2014). Rapid and accurate direct antibiotic susceptibility testing of blood culture broths using MALDI Sepsityper combined with the BD Phoenix automated system. Journal of Medical Microbiology. 87
  • Gray, T. J., Thomas, L., Olma, T., Mitchell, D. H., Iredell, J. R. and Chen, S. C. A. (2014). Rapid Identification of Gram Negative Bacteria from Blood Culture Broth Using MALDI-TOF Mass Spectrometry. Jove-Journal of Visualized Experiments. 2 (54) , 138-145.
  • Guo, X., Dillon, B., Ginn, A., Wiklendt, A., Partridge, S., Iredell, J. (2014). Simple multiplex real-time PCR for rapid detection of common 16S rRNA methyltransferase genes. Diagnostic microbiology and infectious disease. 80 (1) , 29-31. [More Information]
  • Gilroy, N. and Iredell, J. (2014). The clinical and public health challenge of Gram-negative resistance in Australasia. Future Microbiology. 12 (4)
  • Zhou, F., Wang, Q., Sintchenko, V., Gilbert, G., O'Sullivan, M., Iredell, J., Dwyer, D. (2014). Use of the 5' Untranslated Region and VP1 Region to Examine the Molecular Diversity in Enterovirus B Species. Journal of Medical Microbiology. 63 (PT10) , 1339-1355. [More Information]
2013
  • Kok, J., Chen, S. C., Dwyer, D. E. and Iredell, J. R. (2013). Current status of matrix-assisted laser desorption ionisation-time of flight mass spectrometry in the clinical microbiology laboratory. Pathology. Suppl 1 (5) , e4-e4.
  • Kamruzzaman, M., Shoma, S., Naymul Bari, S., Ginn, A., Wiklendt, A., Partridge, S., Faruque, S., Iredell, J. (2013). Genetic diversity and antibiotic resistance in Escherichia coli from environmental surface water in Dhaka City, Bangladesh. Diagnostic Microbiology and Infectious Disease. 76 (2) , 222-226. [More Information]
  • Ginn, A., Zong, Z., Wiklendt, A., Thomas, L., Merlino, J., Gottlieb, T., van Hal, S., Harkness, J., Macleod, C., Bell, S., Partridge, S., Iredell, J., et al (2013). Limited diversity in the gene pool allows prediction of third-generation cephalosporin and aminoglycoside resistance in Escherichia coli and Klebsiella pneumoniae. International Journal of Antimicrobial Agents. 42 (1) , 19-26. [More Information]

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  • Gray, T. J., Thomas, L., Olma, T., Iredell, J. R. and Chen, S. C. A. (2013). Rapid identification of Gram-negative organisms from blood culture bottles using a modified extraction method and MALDI-TOF mass spectrometry. Diagnostic Microbiology and Infectious Disease. (62) , 223-231.
  • Hazelton, B. J., Thomas, L. C., Unver, T. and Iredell, J. R. (2013). Rapid identification of Gram-positive pathogens and their resistance genes from positive blood culture broth using a multiplex tandem RT-PCR assay. Journal of Medical Microbiology. 2 (9) , 115-20.
  • Blyth, C. C., Webb, S. A. R., Kok, J., Dwyer, D. E., van Hal, S. J., Foo, H., Ginn, A. N., Kesson, A. M., Seppelt, I., Iredell, J. R., Investigators, A. I. and Investigators, C. M. (2013). The impact of bacterial and viral co-infection in severe influenza. Influenza and Other Respiratory Viruses. 2 (5) , 119-127.
  • Kok, J., Blyth, C. C., Foo, H., Bailey, M. J., Pilcher, D. V., Webb, S. A., Seppelt, I. M., Dwyer, D. E. and Iredell, J. R. (2013). Viral pneumonitis is increased in obese patients during the first wave of pandemic A(H1N1) 2009 virus. PLoS One. (10)
2012
  • Partridge, S., Iredell, J. (2012). Genetic Contexts of blaNDM-1. Antimicrobial Agents and Chemotherapy. 56 (11) , 6065-6067. [More Information]
  • Partridge, S., Ginn, A., Paulsen, I., Iredell, J. (2012). pEl1573 carrying blaIMP-4, from Sydney, Australia, is closely related to other IncL/M plasmids. Antimicrobial Agents and Chemotherapy. 56 (11) , 6029-6032. [More Information]
  • Partridge, S., Paulsen, I., Iredell, J. (2012). pJIE137 Carrying blaCTX-M-62 Is Closely Related to p271A Carrying blaNDM-1. Antimicrobial Agents and Chemotherapy. 56 (4) , 2166-2168. [More Information]

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  • Ginn, A., Wiklendt, A., Gidding, H., George, N., O'Driscoll, J., Partridge, S., O'Toole, B., Perri, R., Faoagali, J., Gallagher, J., Iredell, J., et al (2012). The Ecology of Antibiotic Use in the ICU: Homogeneous Prescribing of Cefepime but Not Tazocin Selects for Antibiotic Resistant Infection. PloS One. 7 (6) , 1-10. [More Information]
2011
  • Partridge, S., Thomas, L., Ginn, A., Wiklendt, A., Kyme, P., Iredell, J. (2011). A Novel Gene Cassette, aacA43, in a Plasmid-Borne Class 1 Integron. Antimicrobial Agents and Chemotherapy. 55 (6) , 2979-2982. [More Information]
  • Partridge, S., Ellem, J., Tetu, S., Zong, Z., Paulsen, I., Iredell, J. (2011). Complete Sequence of pJIE143, a pir-Type Plasmid Carrying IS Ecp1-blaCTX-M-15 from an Escherichia coli ST131 Isolate. Antimicrobial Agents and Chemotherapy. 55 (12) , 5933-5935. [More Information]
  • Tsafnat, G., Schaeffer, J., Clayphan, A., Iredell, J., Partridge, S., Coiera, E. (2011). Computational inference of grammars for larger-than-gene structures from annotated gene sequences. Bioinformatics. 27 (6) , 791-796. [More Information]

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  • Ellem, J., Partridge, S., Iredell, J. (2011). Efficient Direct Extended-Spectrum B-Lactamase Detection by Multiplex Real-Time PCR: Accurate Assignment of Phenotype by Use of a Limited Set of Genetic Markers. Journal of Clinical Microbiology. 49 (8) , 3074-3077. [More Information]
  • Betteridge, T., Partridge, S., Iredell, J., Stokes, H. (2011). Genetic context and structural diversity of class 1 integrons from human commensal bacteria in a hospital intensive care unit. Antimicrobial Agents and Chemotherapy. 55 (8) , 3939-3943. [More Information]
  • Pinto, A., Halliday, C., Zahra, M., van Hal, S., Olma, T., Maszewska, K., Iredell, J., Meyer, W., Chen, S. (2011). Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Identification of Yeasts Is Contingent on Robust Reference Spectra. PloS One. 6 (10) , e25712-1-e25712-7. [More Information]
  • Partridge, S., Zong, Z., Iredell, J. (2011). Recombination in IS26 and Tn2 in the Evolution of Multi-Resistance Regions Carrying blaCTX-M-15 on Conjugative IncF Plasmids from Escherichia coli. Antimicrobial Agents and Chemotherapy. 55 (11) , 4971-4978. [More Information]
2010
  • Kok, J., Blyth, C. C., Foo, H., Patterson, J., Taylor, J., McPhie, K., Ratnamohan, V. M., Iredell, J. R. and Dwyer, D. E. (2010). Comparison of a rapid antigen test with nucleic acid testing during cocirculation of pandemic influenza A/H1N1 2009 and seasonal influenza A/H3N2. J Clin Microbiol. 6 (192) , 357-8; author reply 357.
  • Zong, Z., Partridge, S., Iredell, J. (2010). ISEcp1-Mediated Transposition and Homologous Recombination Can Explain the Context of blaCTX-M-62 Linked to qnrB2. Antimicrobial Agents and Chemotherapy. 54 (7) , 3039-3042. [More Information]
  • Szewczuk, E., Thapa, K., Anninos, T., McPhie, K., Higgins, G., Dwyer, D. E., Stanley, K. K. and Iredell, J. R. (2010). Rapid semi-automated quantitative multiplex tandem PCR (MT-PCR) assays for the differential diagnosis of influenza-like illness. BMC Infect Dis. 1 (6) , 66-73.

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  • Iredell, J., Partridge, S. (2010). Understanding the Shared Bacterial Genome. Infectious Disease Informatics. , 245-261.
2009
  • Zong, Z., Partridge, S., Iredell, J. (2009). A blaVEB-1 Variant, blaVEB-6, Associated with Repeated Elements in a Complex Genetic Structure. Antimicrobial Agents and Chemotherapy. 53 (4) , 1693-1697. [More Information]
  • Tsafnat, G., Coiera, E., Partridge, S., Schaeffer, J., Iredell, J. (2009). Context-driven discovery of gene cassettes in mobile integrons using a computational grammar. BMC Bioinformatics. 10 , 281-1-281-9. [More Information]
  • Partridge, S., Tsafnat, G., Coiera, E., Iredell, J. (2009). Gene cassettes and cassette arrays in mobile resistance integrons. FEMS Microbiology Reviews. 33 (4) , 757-784. [More Information]

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  • Jiang, X., Espedido, B., Partridge, S., Thomas, L., Wang, F., Iredell, J. (2009). Paradoxical effect of Klebsiella pneumoniae OmpK36 porin deficiency. Pathology. 41 (4) , 388-392. [More Information]
  • Blyth, C. C., Iredell, J. R. and Dwyer, D. E. (2009). Rapid-test sensitivity for novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med. 2 (21) , 339-348.
2008
  • Zong, Z., Lü, X., Valenzuela, J., Partridge, S., Iredell, J. (2008). An outbreak of carbapenem-resistant Acinetobacter baumannii producing OXA-23 carbapenemase in western China. International Journal of Antimicrobial Agents. 31 (1) , 50-54. [More Information]
  • Espedido, B., Partridge, S., Iredell, J. (2008). blaIMP-4 in different genetic contexts in Enterobacteriaceae Isolates from Australia. Antimicrobial Agents and Chemotherapy. 52 (8) , 2984-2987. [More Information]
  • Zong, Z., Partridge, S., Thomas, L., Iredell, J. (2008). Dominance of blaCTX-M within an Australian Extended-Spectrum {beta}-Lactamase Gene Pool. Antimicrobial Agents and Chemotherapy. 52 (11) , 4198-4202. [More Information]

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  • Treerat, P., Widmer, F., Middleton, P. G., Iredell, J. and George, A. M. (2008). In vitro interactions of tobramycin with various nonantibiotics against Pseudomonas aeruginosa and Burkholderia cenocepacia. FEMS Microbiol Lett.. 42064 (105) , 262-271.
  • Lau, A., Sorrell, T., Chen, S., Stanley, K., Iredell, J., Halliday, C. (2008). Multiplex-Tandem PCR: A Novel Platform for the Rapid Detection and Identification of Fungal Pathogens from Blood Culture Specimens. Journal of Clinical Microbiology. 46 (9) , 3021-3027. [More Information]
2007
  • Sintchenko, V., Iredell, J., Gilbert, G. (2007). Pathogen profiling for disease management and surveillance. Nature Reviews Microbiology. 5 (6) , 464-470.
  • Yiasemides, E., Partridge, S., Iredell, J. (2007). RmtC 16S rRNA methyltransferase in Australia.. Antimicrobial Agents and Chemotherapy. 52 , 794-5. [More Information]
2006
  • Valenzuela, J., Thomas, L., Partridge, S., van der Reijden, T., Dijkshoorn, L., Iredell, J. (2006). Horizontal gene transfer within a polyclonal outbreak of carbapenem-resistant Acinetobacter baumannii.. Journal of Clinical Microbiology. 45 (2) , 453-460.
  • Iredell, J., Sintchenko, V. (2006). Screening for antibiotic resistant Gram-negative bacteria. The Lancet Infectious Diseases. 6 , 316-317.
2005
  • Sintchenko, V., Iredell, J., Gilbert, G., Coiera, E. (2005). Handheld computer-based decision support reduces patient length of stay and antibiotic prescribing in critical care.. Journal of the American Medical Informatics Association. 12 (4) , 398-402.
  • Sorrell, T., Mitchell, D., Iredell, J. (2005). Nocardia Species. Principles and Practice of Infectious Diseases. , 2916-2924.
  • Iredell, J., Spelman, D., Sorrell, T. (2005). Septicaemia. Infectious Diseases: A clinical approach. , 183-193.
2004
  • Sintchenko, V., Coiera, E., Iredell, J., Gilbert, G. (2004). Comparative Impact Of Guidelines, Clinical Data, And Decision Support On Prescribing Decisions: An Interactive Web Experiment With Simulated Cases.. Journal of the American Medical Informatics Association. 11 (1) , 71-77.