PhD or Masters

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common genetic cause of kidney failure in adults. It is characterised by the development of multiple cysts in the kidney, which grow through life and destroy kidney tissue. There are no treatments to prevent kidney failure due to ADPKD, and every year in Australia, about 150 people with this condition start dialysis. The aim of this project is to validate and determine the predictive utility of urinary and serum biomarkers (copeptin, MCP-1, FGF-23, polcystin) and their relationship to clinical parameters, MRI-calculated kidney volume and eGFR, as part of a clinical trial in ADPKD.

Supervisor: A/Prof. Gopala Rangan, g.rangan@sydney.edu.au