Herpes Simplex Viral infections cause neonatal and genital herpes and the latter increases the acquisition of HIV by >3 fold. We will examine how HSV2 infection and initial HIV infection is established in skin/mucosa using recently developed human foreskin explant models. The major techniques in this project will be immunofluorescence microscopy and genomics.
Supervisors: Prof. Anthony L. Cunningham and Dr. Min Kim,
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