Publications

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2018
  • Ma, C., Clancy, L., Simms, R., Burgess, J., Deo, S., Blyth, E., Micklethwaite, K., Gottlieb, D. (2018). Adjuvant Peptide Pulsed Dendritic Cell Vaccination in Addition to T Cell Adoptive Immunotherapy for Cytomegalovirus Infection in Allogeneic Hematopoietic Stem Cell Transplantation Recipients. Biology of Blood and Marrow Transplantation. 24 (1) , 71-77. [More Information]
  • Ma, C., Clancy, L., Simms, R., Burgess, J., Deo, S., Blyth, E., Micklethwaite, K., Gottlieb, D. (2018). Adjuvant Peptide Pulsed Dendritic Cell Vaccination in Addition to T Cell Adoptive Immunotherapy for Cytomegalovirus Infection in Allogeneic Hematopoietic Stem Cell Transplantation Recipients. Biology of Blood and Marrow Transplantation. 24 (1) , 71-77. [More Information]
  • Withers, B., Clancy, L., Burgess, J., Simms, R., Brown, R., Micklethwaite, K., Blyth, E., Gottlieb, D. (2018). Establishment and Operation of a Third-Party Virus-Specific T Cell Bank within an Allogeneic Stem Cell Transplant Program. Biology of Blood and Marrow Transplantation. 24 (12) , 2433-2442. [More Information]

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  • Withers, B., Clancy, L., Burgess, J., Simms, R., Brown, R., Micklethwaite, K., Blyth, E., Gottlieb, D. (2018). Establishment and Operation of a Third-Party Virus-Specific T Cell Bank within an Allogeneic Stem Cell Transplant Program. Biology of Blood and Marrow Transplantation. 24 (12) , 2433-2442. [More Information]
  • Gowrishankar, K., Birtwistle, L., Micklethwaite, K. (2018). Manipulating the tumor microenvironment by adoptive cell transfer of CAR T-cells. Mammalian Genome. 29 , 739-757. [More Information]
  • Gowrishankar, K., Birtwistle, L., Micklethwaite, K. (2018). Manipulating the tumor microenvironment by adoptive cell transfer of CAR T-cells. Mammalian Genome. 29 (11-12) , 739-756. [More Information]
  • Bishop, D., Xu, N., Tse, B., O'Brien, T., Gottlieb, D., Dolnikov, A., Micklethwaite, K. (2018). PiggyBac-Engineered T Cells Expressing CD19-Specific CARs that Lack IgG1 Fc Spacers Have Potent Activity against B-ALL Xenografts. Molecular Therapy. 26 (8) , 1883-1895.
  • Bishop, D., Xu, N., Tse, B., O'Brien, T., Gottlieb, D., Dolnikov, A., Micklethwaite, K. (2018). PiggyBac-Engineered T Cells Expressing CD19-Specific CARs that Lack IgG1 Fc Spacers Have Potent Activity against B-ALL Xenografts. Molecular Therapy. 26 (8) , 1883-1895.
  • Kliman, D., Bilmon, I., Kwan, J., Blyth, E., Micklethwaite, K., Panicker, S., Bhattacharyya, A., Deren, S., Antonenas, V., Huang, G., Gottlieb, D. (2018). Rescue haploidentical peripheral blood stem cell transplantation for engraftment failure: a single-centre case series. Internal Medicine Journal. 48 (8) , 988-991. [More Information]
  • Kliman, D., Bilmon, I., Kwan, J., Blyth, E., Micklethwaite, K., Panicker, S., Bhattacharyya, A., Deren, S., Antonenas, V., Huang, G., Gottlieb, D. (2018). Rescue haploidentical peripheral blood stem cell transplantation for engraftment failure: a single-centre case series. Internal Medicine Journal. 48 (8) , 988-991. [More Information]

2017
  • Ma, C., Clancy, L., Deo, S., Blyth, E., Micklethwaite, K., Gottlieb, D. (2017). Herpes simplex virus type 1 (HSV-1) specific T-cell generation from HLA-A1- and HLA-A2-positive donors for adoptive immunotherapy. Cytotherapy. 19 (1) , 107-118. [More Information]
  • Withers, B., Blyth, E., Clancy, L., Yong, A., Fraser, C., Burgess, J., Simms, R., Brown, R., Kliman, D., Dubosq, M., Bishop, D., Sutrave, G., Ma, C., Shaw, P., Micklethwaite, K., Gottlieb, D. (2017). Long-term control of recurrent or refractory viral infections after allogeneic HSCT with third-party virus-specific T cells. Artificial Cells, Blood Substitutes, and Biotechnology. 1 (24) , 2193-2205. [More Information]
  • Withers, B., Blyth, E., Clancy, L., Yong, A., Fraser, C., Burgess, J., Simms, R., Brown, R., Kliman, D., Dubosq, M., Bishop, D., Sutrave, G., Ma, C., Shaw, P., Micklethwaite, K., Gottlieb, D. (2017). Long-term control of recurrent or refractory viral infections after allogeneic HSCT with third-party virus-specific T cells. Artificial Cells, Blood Substitutes, and Biotechnology. 1 (24) , 2193-2205. [More Information]

2016
  • Kong, B., Micklethwaite, K., Swaminathan, S., Kefford, R., Carlino, M. (2016). Autoimmune hemolytic anemia induced by anti-PD-1 therapy in metastatic melanoma. Melanoma Research. 26 (2) , 202-204. [More Information]

2015
  • Ma, C., Blyth, E., Clancy, L., Simms, R., Burgess, J., Brown, R., Deo, S., Micklethwaite, K., Gottlieb, D. (2015). Addition of varicella zoster virus-specific T cells to cytomegalovirus, Epstein-Barr virus and adenovirus tri-specific T cells as adoptive immunotherapy in patients undergoing allogeneic hematopoietic stem cell transplantation. Cytotherapy. 17 (10) , 1406-1420. [More Information]
  • Macesic, N., Langsford, D., Nicholls, K., Hughes, P., Gottlieb, D., Clancy, L., Blyth, E., Micklethwaite, K., Withers, B., Majumdar, S., et al (2015). Adoptive T cell immunotherapy for treatment of ganciclovir-resistant cytomegalovirus disease in a renal transplant recipient. American Journal Of Transplantation. 15 (3) , 827-832. [More Information]
  • Dolnikov, A., Shen, S., Klamer, G., Joshi, S., Xu, N., Yang, L., Micklethwaite, K., O'Brien, T. (2015). Anti-leukemic potency of CD19-specific T cells against chemoresistant paediatric acute lymphoblastic leukaemia. Experimental Hematology. 43 (12) , 1001-1014. [More Information]

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  • Bradstock, K., Bilmon, I., Kwan, J., Blyth, E., Micklethwaite, K., Huang, G., Deren, S., Byth Wilson, K., Gottlieb, D. (2015). Influence of Stem Cell Source on Outcomes of Allogeneic Reduced Intensity Conditioning Therapy Transplants Using Haploidentical Related Donors. Biology of Blood and Marrow Transplantation. 21 (9) , 1641-1645. [More Information]
  • Ramanayake, S., Bilmon, I., Bishop, D., Dubosq, M., Blyth, E., Clancy, L., Gottlieb, D., Micklethwaite, K. (2015). Low-cost generation of Good Manufacturing Practice-grade CD19-specific chimeric antigen receptor-expressing T cells using piggyBac gene transfer and patient-derived materials. Cytotherapy. 17 (9) , 1251-1267. [More Information]
  • Bradstock, K., Bilmon, I., Kwan, J., Micklethwaite, K., Blyth, E., Deren, S., Bayley, A., Gebski, V., Gottlieb, D. (2015). Single-agent high-dose cyclophosphamide for graft-versus-host disease prophylaxis in human leukocyte antigen-matched reduced-intensity peripheral blood stem cell transplantation results in an unacceptably high rate of severe acute graft-versus-host disease. Biology of Blood and Marrow Transplantation. 21 (5) , 941-944. [More Information]

2013
  • Clancy, L., Blyth, E., Simms, R., Micklethwaite, K., Ma, C., Burgess, J., Antonenas, V., Shaw, P., Gottlieb, D. (2013). Cytomegalovirus-specific cytotoxic T lymphocytes can be efficiently expanded from granulocyte colony-stimulating factor-mobilized hemopoietic progenitor cell products ex vivo and safely transferred to stem cell transplantation recipients to facilitate immune reconstitution. Biology of Blood and Marrow Transplantation. 19 (5) , 725-734. [More Information]
  • Blyth, E., Clancy, L., Simms, R., Ma, C., Burgess, J., Deo, S., Byth Wilson, K., Dubosq, M., Shaw, P., Micklethwaite, K., Gottlieb, D. (2013). Donor-derived CMV specific T-cells reduce the requirement for CMV-directed pharmacotherapy after allogeneic stem cell transplantation. Blood. 121 (18) , 3745-3758. [More Information]
  • Cruz, C., Micklethwaite, K., Savoldo, B., Ramos, C., Lam, S., Ku, S., Diouf, O., Liu, E., Barrett, A., Ito, S., et al (2013). Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: a phase 1 study. Blood. 122 (17) , 2965-2973. [More Information]

2012
  • Blyth, E., Deo, S., Clancy, L., Simms, R., Bilmon, I., Micklethwaite, K., Gottlieb, D. (2012). Clinical-grade varicella zoster virus-specific T cells produced for adoptive immunotherapy in hemopoietic stem cell transplant recipients. Cytotherapy. 14 (6) , 724-732. [More Information]

2011
  • Blyth, E., Clancy, L., Simms, R., Deo, S., O'Connell, P., Micklethwaite, K., Gottlieb, D. (2011). BK Virus-Specific T Cells for Use in Cellular Therapy Show Specificity to Multiple Antigens and Polyfunctional Cytokine Responses. Transplantation. 92 (10) , 1077-1084. [More Information]

2010
  • Micklethwaite, K., Savoldo, B., Hanley, P., Leen, A., Demmler-Harrison, G., Cooper, L., Liu, H., Gee, A., Shpall, E., Rooney, C., et al (2010). Derivation of human T lymphocytes from cord blood and peripheral blood with antiviral and antileukemic specificity from a single culture as protection against infection and relapse after stem cell transplantation. Blood. 115 (13) , 2695-2703. [More Information]

2009
  • Micklethwaite, K., Garvin, F., Kariotis, M., Yee, L., Hansen, A., Antonenas, V., Sartor, M., Turtle, C., Gottlieb, D. (2009). Clinical-scale elutriation as a means of enriching antigen-presenting cells and manipulating alloreactivity. Cytotherapy. 11 (2) , 218-228. [More Information]

2008
  • Micklethwaite, K., Clancy, L., Sandher, U., Hansen, A., Blyth, E., Antonenas, V., Sartor, M., Bradstock, K., Gottlieb, D. (2008). Prophylactic infusion of cytomegalovirus specific cytotoxic T-lymphocytes stimulated with Ad5f35pp65 gene modified dendritic cells following allogeneic haemopoietic stem cell transplantation. Blood. 112 (10) , 3974-3981. [More Information]

2007
  • Micklethwaite, K., Hansen, A., Foster, A., Snape, E., Antonenas, V., Sartor, M., Shaw, P., Bradstock, K., Gottlieb, D. (2007). Ex vivo expansion and prophylactic infusion of CMV-pp65 peptide-specific cytotoxic T-lymphocytes following allogeneic hematopoietic stem cell transplantation. Biology of Blood and Marrow Transplantation. 13 (6) , 707-714. [More Information]
  • Gottlieb, D., Micklethwaite, K., Bradstock, K., Li, Y. (2007). Rapid expansion of tumor-reactive cells from HLA-matched siblings for adoptive immunotherapy of melanoma. Cytotherapy. 9 (2) , 133-143.

2006
  • Hansen, A., Micklethwaite, K., Foster, A., Bradstock, K., Gottlieb, D. (2006). Ex vivo expansion of clinical grade CMV specific CTL for therapeutic use in allogeneic haemopoietic stem cell transplantation. 2nd International Conference 'Strategies in Tissue Engineering'.