Projects

  • Roles of matrix metalloproteinases (MMPs), E-cadherin, beta-catenin, transforming growth factor (TGF-beta), epithelial & endothelial-mesenchymal transition in pathogenesis of kidney fibrosis.
  • Targeting β-catenin/Foxo to maximize anti-inflammatory and wound healing effects while preventing profibrotic effects of TGF-β as a novel treatment of chronic kidney diseases.