About
- WIMR brings together some of the brightest minds to deliver real and significant research breakthroughs for many of the most serious illnesses, improving health and saving lives in Australia and around the world, because people’s lives matter.
Research
- WIMR is home to more than 45 research groups concerned with a wide range of human diseases and conditions. Key to our success is the way we connect researchers, clinicians and supporters.
People
Careers
- Excellent scientific results require exceptional people.
Students
- Students are a fundamental part of research activity at The Westmead Institute. We give our students the opportunity to do important work that is closely linked to the needs of patients.
Outcomes
- The needs of patients are central to everything we do at WIMR. Our research is highly translational. We are passionate about putting our findings into practice and giving hope to those who need it most.
  - Our Discoveries
  - Case Studies
Support Us
- We save lives. You can too. While medical research receives support from governments, some worthwhile projects miss out on receiving grants. Your generosity can help us bridge this gap and translate laboratory discoveries into clinical practice where they can give new hope.

About
- WIMR brings together some of the brightest minds to deliver real and significant research breakthroughs for many of the most serious illnesses, improving health and saving lives in Australia and around the world, because people’s lives matter.
Research
- WIMR is home to more than 45 research groups concerned with a wide range of human diseases and conditions. Key to our success is the way we connect researchers, clinicians and supporters.
People
Careers
- Excellent scientific results require exceptional people.
Students
- Students are a fundamental part of research activity at The Westmead Institute. We give our students the opportunity to do important work that is closely linked to the needs of patients.
Outcomes
- The needs of patients are central to everything we do at WIMR. Our research is highly translational. We are passionate about putting our findings into practice and giving hope to those who need it most.
  - Our Discoveries
  - Case Studies
Support Us
- We save lives. You can too. While medical research receives support from governments, some worthwhile projects miss out on receiving grants. Your generosity can help us bridge this gap and translate laboratory discoveries into clinical practice where they can give new hope.

Associate Professor Gopala RanganAssociate Professor (Conjoint); Medicine, Westmead Clinical School; The Westmead Institute for Medical Research - Polycystic Kidney Disease Group
Phone+61 2 9845 6962

Fax+61 2 9633 9351

Emailg.rangan(at)sydney.edu.au

Cyclin Dependent Kinases As Drug-Targets To Reduce Renal Cyst Formation and Scarring in PKD.
Vitamin D3 receptor signalling to prevent kidney failure due to PKD.
NF-kappaB as a therapeutic target in PKD.
Controlled trial of slowing kidney disease progression from the inhibition of xanthine oxidase (CKD-FIX) (funded by NHMRC).
Randomised controlled trial to determine the safety and efficacy of prescribed water intake to prevent kidney failure due to ADPKD (PREVENT-ADPKD).
Multi-centre, open-label, extension study to evaluate the long-term efficacy and safety of oral tolvaptan tablet regimens in subjects with ADPKD (REPRISE/TEMPO) (Otsuka).

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Keep up-to-date with the latest news from The Westmead Institute, including research findings, new discoveries and stories of hope.

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