A Prof Douglas is an Infectious Diseases Physician and molecular virologist, with a strong research interest in viral hepatitis. After completing a PhD in virology he undertook a NHMRC CJ Martin Postdoctoral Fellowship on hepatitis C virus (HCV) at the prestigious MRC Virology Unit in the UK, working with Dr John McLauchlan. He now heads the Viral Hepatitis Pathogenesis group at Storr Liver Unit, Westmead Millennium Institute, with a broad range of projects ranging from basic molecular pathogenesis to clinical research. He runs a hepatitis clinic at Blacktown Hospital, treating patients with Chronic Hepatitis B and Hepatitis C, and also sees patients at Westmead Hospital with a range of Infectious Diseases.
The overall aim of his research is to improve the health and well being of people with chronic viral infections.
I am an Infectious Diseases Physician and molecular virologist, with a strong research interest in viral hepatitis.I run a research group at the Westmead Millennium Institute studying hepatitis B virus (HBV) and hepatitis C virus (HCV), with a broad range of projects ranging from basic molecular pathogenesis to clinical research.
I run a hepatitis treatment clinic in Western Sydney, treating patents with chronic Hepatitis B and Hepatitis C, as well as a general Infectious Diseases and HIV clinic.
My current research projects include:
1. Interactions between HCV and cellular lipid pathways.
2. Effects of HCV on the innate antiviral response, including cellular interferons.
3. Mechanisms of HCV replication.
4. Antiviral resistance for HBV and HCV.
5. Factors that affect adherence to antiviral treatment, and how to improve this.
6. How to improve treatment access and support for people from socially disadvantaged groups.
My overall aim is to improve the health and wellbeing of people with chronic viral infections.
Hepatology, Diabetes, Lipid metabolism, Hepatitis, Virology
Obesity, Diabetes and Cardiovascular Disease, Infection and Immunological Conditions, Healthy Ageing
Gastroenterology and Hepatology