Biography

I am a senior staff specialist at Westmead Hospital, and Clinical Associate Professor in Medicine for the University of Sydney. 

Research focus

My research aims to identify and solve problems related to people with chronic kidney disease. This is done using several strategies, including benchside scientific work, analysis of data from observational studies and registries, and clinical trials.

Current directions in my research include:

- Evaluating the benefits and harms of using technology to optimise health in people with chronic kidney disease

- Identifying ways of helping people with chronic kidney disease during pregnancy

- Identifying molecular mechanisms for progression of chronic kidney disease and its most significant extrarenal complication - cardiovascular disease.
 

Publications

  1. Rangan GK, Wong ATY, Munt A, Zhang JQJ, Saravanabavan S, Louw S, Allman-Farinelli M, Badve SV, Boudville N, Chan J, Coolican H, Coulshed S, Edwards ME, Erickson BJ, Fernando M, Foster S, Gregory AV, Haloob I, Hawley CM, Holt J, Howard K, Howell M, Johnson DW, Kline TL, Kumar K, Lee VW, Lonergan M, Mai J, McCloud P, Pascoe E, Peduto A, Rangan A, Roger SD, Sherfan J, Sud K, Torres VE, Vilayur E, Harris DCH. Prescribed Water Intake in Autosomal Dominant Polycystic Kidney Disease. NEJM Evidence. 2022;1(1):EVIDoa2100021.
  2. Zen M, Marschner S, Szczeklik W, Roshanov PS, Alahakoon TI, Chow C, Devereaux PJ, McDonald SD, Lee VW. Association of Preeclampsia with Myocardial Injury Among Patients Undergoing Noncardiac Surgery: the PREECLAMPSIA-VISION study. Can J Cardiol. 2021 Jun 26;. doi: 10.1016/j.cjca.2021.06.012. [Epub ahead of print] PubMed PMID: 34182021.  
  3. Dawson J, Campbell KL, Craig JC, Tong A, Teixeira-Pinto A, Brown MA, Howard K, Howell M, Khalid R, Sud K, Thiagalingam A, Chow CK, Lee VW. A Text Messaging Intervention for Dietary Behaviors for People Receiving Maintenance Hemodialysis: A Feasibility Study of KIDNEYTEXT. Am J Kidney Dis. 2021 Jan 6;. doi: 10.1053/j.ajkd.2020.11.015. [Epub ahead of print] PubMed PMID: 33421456. 
  4. Wang J, Lewis JR, Byrnes E, Wong G, Raymond WD, Zhu K, Robertson GR, Lim WH, Cao Q, Prince RL, Lee VW.  Serum Midkine, estimated glomerular filtration rate and chronic kidney disease-related events in elderly women: Perth Longitudinal Study of Aging Women. Sci Rep. 2020 Sep 2;10(1):14499. doi: 10.1038/s41598-020-71353-8. PMID: 32879333
  5. Chen T, Cao Q, Wang R, Zheng G, Azmi F, Wang J, Lee VW, Wang YM, Yu H, Patel M, P'ng CH, Alexander SI, Rogers NM, Wang Y, Harris DCH. Conventional Type 1 Dendritic Cells (cDC1) in Human Kidney Diseases: Clinico-Pathological Correlations. Front Immunol. 2021;12:635212. doi: 10.3389/fimmu.2021.635212. eCollection 2021. PubMed PMID: 34054804; PubMed Central PMCID: PMC8149958.
  6. Stevenson JK, Campbell ZC, Webster AC, Chow CK, Tong A, Craig JC, Campbell KL, Lee VW. eHealth interventions for people with chronic kidney disease. Cochrane Database Syst Rev. 2019 Aug 6;8:CD012379. doi: 10.1002/14651858.CD012379.pub2.
  7. Stevenson J, Tong A, Gutman T, Campbell KL, Craig JC, Brown MA, Lee VW. Experiences and Perspectives of Dietary Management Among Patients on Hemodialysis: An Interview Study. J Ren Nutr. 2018;28(6):411-21. 
  8. Padmanabhan S, Lee VW, McLean M, Athayde N, Lanzarone V, Khoshnow Q, Peek MJ, Cheung NW. The Association of Falling Insulin Requirements With Maternal Biomarkers and Placental Dysfunction: A Prospective Study of Women With Preexisting Diabetes in Pregnancy. Diabetes Care. 2017;40(10):1323-30. Epub 2017/08/12. doi: 10.2337/dc17-0391. PubMed PMID: 28798085.
  9. Lee VW, Harris DC. Adriamycin nephropathy: a model of focal segmental glomerulosclerosis. Nephrology (Carlton). 2011;16(1):30-8. Epub 2010/12/24. doi: 10.1111/j.1440-1797.2010.01383.x. PubMed PMID: 21175974.
  10. Alahakoon TI, Medbury H, Williams H, Fewings N, Wang XM, Lee VW.  Distribution of monocyte subsets and polarization in preeclampsia and intrauterine fetal growth restriction. J Obstet Gynaecol Res. 2018;44(12):2135-48. Epub 2018/07/31. doi: 10.1111/jog.13770. PubMed PMID: 30058176.
Keywords

chronic kidney disease, digital health, preeclampsia, vascular calcification

Clinical Specialty

Nephrology

Other Affiliations

Academic lead, University of Sydney

Clinical Lead, Renal Pregnancy services, Westmead Hospital

Director of Dialysis, Norwest Private Hospital

Education

MBBS (first class honours), The University of Sydney, 1995
FRACP 2005
PhD, The University of Sydney, 2010