Dinny Graham completed her PhD in the Department of Medical Oncology, University of Sydney at Westmead Hospital, studying the transcriptional targets of progesterone in breast cancer. She was awarded a NHMRC CJ Martin Fellowship to travel to Denver, Colorado, USA, to complete a postdoctoral fellowship in the laboratory of Professor Kathryn Horwitz, where she investigated the role of nuclear receptor coregulators in endocrine resistance. She has a number of publications arising from her postdoctoral years, including a major study on a new steroid receptor chaperone, which she first cloned. During her time in the United States, Dinny was awarded grants from the Cancer League of Colorado and the Susan G Komen Breast Cancer Foundation, in addition to a Department of Defense Postdoctoral Fellowship Award.
Dinny returned to Australia to work with Professor Christine Clarke in the Breast Cancer Group at the Westmead Institute for Cancer Research (WICR) in mid-2001, and has effectively initiated productive new areas of research in the laboratory. She leads the molecular genomics program in the group, examining molecular mechanisms of nuclear receptor action. She has been instrumental in developing high throughput genomic analysis methods in the laboratory and plays an active role in the broader genomics community at Westmead. She co-chairs the Westmead Hub Genomics Committee, and was a driver in establishing gene expression profiling and next-generation sequencing capability in the Westmead Institute Genomics Facility. She is a member of the Westmead Institute Faculty and chairs the Westmead Institute Seminars & Training Committee.
Nuclear receptors, Breast cancer, Endocrinology, Molecular biology, Computational biology