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Publications

Dr Grant ParnellResearch Fellow, Centre for Immunology and Allergy Research; Honorary Research Fellow, Sydney Medical School – Westmead, The University of Sydney
+61286273604

Publications

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2019
  • Afrasiabi, A., Parnell, G., Fewings, N., Schibeci, S., Basuki, M., Zhou, Y., Chandramohan, R., Taylor, B., Brown, D., Swaminathan, S., McKay, F., Stewart, G., Booth, D. (2019). Evidence from genome wide association studies implicates reduced control of Epstein-Barr virus infection in multiple sclerosis susceptibility. Genome Medicine. 11 (1) , 1-13. [More Information]
  • Afrasiabi, A., Parnell, G., Fewings, N., Schibeci, S., Basuki, M., Zhou, Y., Chandramohan, R., Taylor, B., Brown, D., Swaminathan, S., McKay, F., Stewart, G., Booth, D. (2019). Evidence from genome wide association studies implicates reduced control of Epstein-Barr virus infection in multiple sclerosis susceptibility. Genome Medicine. 11 (1) , 1-13. [More Information]
  • Parnell, G., Brown, D., Liddle, C., Stewart, G., Booth, D., Schibeci, S., Fewings, N., Afrasiabi, A., Samaranayake, S., Law, S., Kh'ng, J., Fong, Y. (2019). The latitude-dependent autoimmune disease risk genes ZMIZ1 and IRF8 regulate mononuclear phagocytic cell differentiation in response to vitamin D. Human Molecular Genetics. 28 (2) , 269-278. [More Information]

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  • Parnell, G., Brown, D., Liddle, C., Stewart, G., Booth, D., Schibeci, S., Fewings, N., Afrasiabi, A., Samaranayake, S., Law, S., Kh'ng, J., Fong, Y. (2019). The latitude-dependent autoimmune disease risk genes ZMIZ1 and IRF8 regulate mononuclear phagocytic cell differentiation in response to vitamin D. Human Molecular Genetics. 28 (2) , 269-278. [More Information]
2018
  • Wirasinha, R., Vijayan, D., Smith, N., Parnell, G., Swarbrick, A., Brink, R., King, C., Stewart, G., Booth, D., Batten, M. (2018). GPR65 inhibits experimental autoimmune encephalomyelitis through CD4+ T cell independent mechanisms that include effects on iNKT cells. Immunology and Cell Biology. 96 (2) , 128-136. [More Information]
  • Wirasinha, R., Vijayan, D., Smith, N., Parnell, G., Swarbrick, A., Brink, R., King, C., Stewart, G., Booth, D., Batten, M. (2018). GPR65 inhibits experimental autoimmune encephalomyelitis through CD4+ T cell independent mechanisms that include effects on iNKT cells. Immunology and Cell Biology. 96 (2) , 128-136. [More Information]
  • Read, S., Parnell, G., Booth, D., Douglas, M., George, J., Ahlenstiel, G. (2018). The antiviral role of zinc and metallothioneins in hepatitis C infection. Journal of Viral Hepatitis. 25 (5) , 491-501. [More Information]

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  • Read, S., Parnell, G., Booth, D., Douglas, M., George, J., Ahlenstiel, G. (2018). The antiviral role of zinc and metallothioneins in hepatitis C infection. Journal of Viral Hepatitis. 25 (5) , 491-501. [More Information]
2017
  • Fewings, N., Gatt, P., McKay, F., Parnell, G., Schibeci, S., Edwards, J., Basuki, M., Goldinger, A., Fabis-Pedrini, M., Kermode, A., Burke, T., Vucic, S., Stewart, G., Booth, D., et al (2017). Data characterizing the ZMIZ1 molecular phenotype of multiple sclerosis. Data in Brief. 11 , 364-370. [More Information]
  • Fewings, N., Gatt, P., McKay, F., Parnell, G., Schibeci, S., Edwards, J., Basuki, M., Goldinger, A., Fabis-Pedrini, M., Kermode, A., Burke, T., Vucic, S., Stewart, G., Booth, D., et al (2017). Data characterizing the ZMIZ1 molecular phenotype of multiple sclerosis. Data in Brief. 11 , 364-370. [More Information]
  • Fewings, N., Gatt, P., McKay, F., Parnell, G., Schibeci, S., Edwards, J., Basuki, M., Goldinger, A., Fabis-Pedrini, M., Kermode, A., Burke, T., Vucic, S., Stewart, G., Booth, D., et al (2017). The autoimmune risk gene ZMIZ1 is a vitamin D responsive marker of a molecular phenotype of multiple sclerosis. Journal of Autoimmunity. 78 , 57-69. [More Information]

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  • Fewings, N., Gatt, P., McKay, F., Parnell, G., Schibeci, S., Edwards, J., Basuki, M., Goldinger, A., Fabis-Pedrini, M., Kermode, A., Burke, T., Vucic, S., Stewart, G., Booth, D., et al (2017). The autoimmune risk gene ZMIZ1 is a vitamin D responsive marker of a molecular phenotype of multiple sclerosis. Journal of Autoimmunity. 78 , 57-69. [More Information]
  • Parnell, G., Booth, D. (2017). The Multiple Sclerosis (MS) genetic risk factors indicate both acquired and innate immune cell subsets contribute to MS pathogenesis and identify novel therapeutic opportunities. Colegio de Farmaceuticos de la Provincia de Buenos Aires. 8 (ARP) , 1-6. [More Information]
  • Parnell, G., Booth, D. (2017). The Multiple Sclerosis (MS) genetic risk factors indicate both acquired and innate immune cell subsets contribute to MS pathogenesis and identify novel therapeutic opportunities. Colegio de Farmaceuticos de la Provincia de Buenos Aires. 8 (ARP) , 1-6. [More Information]
  • Parnell, G., Booth, D. (2017). The Multiple Sclerosis (MS) genetic risk factors indicate both acquired and innate immune cell subsets contribute to MS pathogenesis and identify novel therapeutic opportunities. Frontiers in Immunology. 8 , 1-6. [More Information]
2016
  • Booth, D., Ding, N., Parnell, G., Shahijanian, F., Coulter, S., Schibeci, S., Atkins, A., Stewart, G., Evans, R., Downes, M., Liddle, C. (2016). Cistromic and genetic evidence that the vitamin D receptor mediates susceptibility to latitude-dependent autoimmune diseases. Genes and Immunity. 17 (4) , 213-219. [More Information]
  • Booth, D., Fewings, N., Parnell, G., McKay, F., Stewart, G. (2016). Differences in common heritable blood immune cell populations may underlie MS susceptibility and progression. Multiple Sclerosis Journal - Experimental, Translational and Clinical. 2 , 1-4. [More Information]
  • Booth, D., Fewings, N., Parnell, G., McKay, F., Stewart, G. (2016). Differences in common heritable blood immune cell populations may underlie MS susceptibility and progression. Multiple Sclerosis Journal - Experimental, Translational and Clinical. 2 , 1-4. [More Information]

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  • McKay, F., Gatt, P., Fewings, N., Parnell, G., Schibeci, S., Basuki, M., Powell, J., Goldinger, A., Fabis-Pedrini, M., Kermode, A., Burke, T., Vucic, S., Stewart, G., Booth, D. (2016). The low EOMES/TBX21 molecular phenotype in multiple sclerosis reflects CD56+ cell dysregulation and is affected by immunomodulatory therapies. Clinical Immunology. 163 , 96-107. [More Information]
  • Nalos, M., Parnell, G., Robergs, R., Booth, D., McLean, A., Tang, B. (2016). Transcriptional reprogramming of metabolic pathways in critically ill patients. Intensive Care Medicine Experimental. 4 (21) , 1-15. [More Information]
  • Nalos, M., Parnell, G., Robergs, R., Booth, D., McLean, A., Tang, B. (2016). Transcriptional reprogramming of metabolic pathways in critically ill patients. Intensive Care Medicine Experimental. 4 , 1-15. [More Information]
  • Nalos, M., Parnell, G., Robergs, R., Booth, D., McLean, A., Tang, B. (2016). Transcriptional reprogramming of metabolic pathways in critically ill patients. Intensive Care Medicine Experimental. 4 , 1-15. [More Information]
2015
  • Field, J., Shahijanian, F., Schibeci, S., Johnson, L., Gresle, M., Laverick, L., Parnell, G., Stewart, G., McKay, F., Kilpatrick, T., Booth, D., et al (2015). The MS Risk Allele of CD40 Is Associated with Reduced Cell-Membrane Bound Expression in Antigen Presenting Cells: Implications for Gene Function. PloS One. 10 (6) , 1-4. [More Information]
  • Field, J., Shahijanian, F., Schibeci, S., Johnson, L., Gresle, M., Laverick, L., Parnell, G., Stewart, G., McKay, F., Kilpatrick, T., Booth, D., et al (2015). The MS Risk Allele of CD40 Is Associated with Reduced Cell-Membrane Bound Expression in Antigen Presenting Cells: Implications for Gene Function. PloS One. 10 (6) , 1-4. [More Information]
  • Field, J., Shahijanian, F., Schibeci, S., Johnson, L., Gresle, M., Laverick, L., Parnell, G., Stewart, G., McKay, F., Kilpatrick, T., Booth, D., et al (2015). The MS Risk Allele of CD40 Is Associated with Reduced Cell-Membrane Bound Expression in Antigen Presenting Cells: Implications for Gene Function.. PloS One. 10 (6) , e0127080. [More Information]
2014
  • O'Connor, K., Parnell, G., Patrick, E., Ahlenstiel, G., Suppiah, V., van der Poorten, D., Read, S., Leung, R., Douglas, M., Yang, J., Stewart, G., Liddle, C., George, J., Booth, D. (2014). Hepatic metallothionein expression in chronic hepatitis C virus infection is IFNL3 genotype-dependent. Genes and Immunity. 15 (2) , 88-94. [More Information]
  • Parnell, G., Gatt, P., McKay, F., Schibeci, S., Krupa, M., Powell, J., Visscher, P., Montgomery, G., Lechner-Scott, J., Broadley, S., Liddle, C., Vucic, S., Stewart, G., Booth, D., et al (2014). Ribosomal protein S6 mRNA is a biomarker upregulated in multiple sclerosis, downregulated by interferon treatment, and affected by season. Multiple Sclerosis Journal. 20 (6) , 675-685. [More Information]
  • Parnell, G., Gatt, P., Krupa, M., Dorothee, N., McKay, F., Schibeci, S., Batten, M., Baranzini, S., Henderson, A., Barnett, M., Vucic, S., Stewart, G., Booth, D., et al (2014). The autoimmune disease-associated transcription factors EOMES and TBX21 are dysregulated in multiple sclerosis and define a molecular subtype of disease. Clinical Immunology. 151 (1) , 16-24. [More Information]

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  • Shahijanian, F., Parnell, G., McKay, F., Gatt, P., Shojaei, M., O'Connor, K., Schibeci, S., Brilot-Turville, F., Liddle, C., Batten, M., Stewart, G., Booth, D. (2014). The CYP27B1 variant associated with an increased risk of autoimmune disease is underexpressed in tolerizing dendritic cells. Human Molecular Genetics. 23 (6) , 1425-1434. [More Information]
  • Shahijanian, F., Parnell, G., McKay, F., Gatt, P., Shojaei, M., O'Connor, K., Schibeci, S., Brilot-Turville, F., Liddle, C., Batten, M., Stewart, G., Booth, D. (2014). The CYP27B1 variant associated with an increased risk of autoimmune disease is underexpressed in tolerizing dendritic cells. Human Molecular Genetics. 23 (6) , 1425-1434. [More Information]
  • Shahijanian, F., Parnell, G., McKay, F., Gatt, P., Shojaei, M., O'Connor, K., Schibeci, S., Brilot-Turville, F., Liddle, C., Batten, M., Stewart, G., Booth, D. (2014). The CYP27B1 variant associated with increased risk of autoimmune disease is underexpressed in tolerising dendritic cells. Human Molecular Genetics. 23 (6) , 1425-1434. [More Information]
  • Parnell, G., Booth, D. (2014). Whole Blood Transcriptomic Analysis to Identify Clinical Biomarkers of Drug Response. Pharmacogenomics in Drug Discovery and Development. , 35-43.
2013
  • Nanan, B., Straubinger, K., Hsu, P., Parnell, G., Tang, B., Xu, B., Makris, A., Hennessy, A., Peek, M., Busch, D., Nanan, R., et al (2013). Fetal-maternal alignment of regulatory T cells correlates with IL-10 and Bcl-2 upregulation in pregnancy. The Journal of Immunology. 191 (1) , 145-153. [More Information]
  • Parnell, G., Tang, B., Nalos, M., Armstrong, N., Huang, S., Booth, D., McLean, A. (2013). Identifying key regulatory genes in the whole blood of septic patients to monitor underlying immune dysfunctions. Shock. 40 (3) , 166-174. [More Information]
  • McKay, F., Hoe, E., Parnell, G., Gatt, P., Schibeci, S., Stewart, G., Booth, D. (2013). IL7Ralpha Expression and Upregulation by IFNbeta in Dendritic Cell Subsets Is Haplotype-Dependent. PloS One. 8 (10) , 1-10. [More Information]
2012
  • Parnell, G., McLean, A., Booth, D., Armstrong, N., Nalos, M., Huang, S., Manak, J., Tang, W., Tam, O., Chan, S., Tang, B. (2012). A distinct influenza infection signature in the blood transcriptome of patients with severe community-acquired pneumonia. Critical Care. 16 (4) , 1-12. [More Information]
  • Nalos, M., Nanan, B., Parnell, G., Tang, B., McLean, A., Nanan, R. (2012). Immune effects of interferon gamma in persistent staphylococcal sepsis. American Journal of Respiratory and Critical Care Medicine. 185 (1) , 110-112.
2011
  • Parnell, G., McLean, A., Booth, D., Huang, S., Nalos, M., Tang, B. (2011). Aberrant Cell Cycle and Apoptotic Changes Characterise Severe Influenza A Infection - A Meta-Analysis of Genomic Signatures in Circulating Leukocytes. PloS One. 6 (3) , e17186-1-e17186-10. [More Information]