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2017
  • Tang, B., Shojaei, M., Parnell, G., Huang, S., Nalos, M., Teoh, S., O'Connor, K., Schibeci, S., Phu, A., Kumar, A., Luo, H., Booth, D., McLean, A., et al (2017). A novel immune biomarker IFI27 discriminates between influenza and bacteria in patients with suspected respiratory infection. European Respiratory Journal. 49 (6) , 1-12. [More Information]
  • Jones, A., Trend, S., Byrne, S., Fabis-Pedrini, M., Geldenhuys, S., Nolan, D., Booth, D., Carroll, W., Lucas, R., Kermode, A., et al (2017). Altered regulatory T-cell fractions and Helios expression in clinically isolated syndrome: clues to the development of multiple sclerosis. Clinical & Translational Immunology. 6 (5) , 1-10. [More Information]
  • Fewings, N., Gatt, P., McKay, F., Parnell, G., Schibeci, S., Edwards, J., Basuki, M., Goldinger, A., Fabis-Pedrini, M., Kermode, A., Burke, T., Vucic, S., Stewart, G., Booth, D., et al (2017). Data characterizing the ZMIZ1 molecular phenotype of multiple sclerosis. Data in Brief. 11 , 364-370. [More Information]

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  • Trend, S., Jones, A., Geldenhuys, S., Byrne, S., Fabis-Pedrini, M., Nolan, D., Booth, D., Carroll, W., Lucas, R., Kermode, A., et al (2017). Evolving identification of blood cells associated with clinically isolated syndrome: Importance of time since clinical presentation and diagnostic MRI. International Journal of Molecular Sciences. 18 (6) , 1-17. [More Information]
  • Eslam, M., McLeod, D., Kelaeng, K., Mangia, A., Berg, T., Thabet, K., Irving, W., Dore, G., Sheridan, D., Gronbaek, H., Booth, D., Weltman, M., Douglas, M., Liddle, C., George, J., et al (2017). IFN-(lambda)3, not IFN-(lambda)4, likely mediates IFNL3-IFNL4 haplotype-dependent hepatic inflammation and fibrosis. Nature Genetics. 49 (5) , 795-800. [More Information]
  • Hart, P., Lucas, R., Booth, D., Carroll, W., Nolan, D., Cole, J., Jones, A., Kermode, A. (2017). Narrowband UVB phototherapy for clinically isolated syndrome: A trial to deliver the benefits of vitamin D and other UVB-induced molecules. Frontiers in Immunology. 8 , 1-6. [More Information]
  • Hart, P., Lucas, R., Booth, D., Carroll, W., Nolan, D., Cole, J., Jones, A., Kermode, A. (2017). Narrowband UVB phototherapy for clinically isolated syndrome: A trial to deliver the benefits of vitamin D and other UVB-induced molecules. Frontiers in Immunology. 8 (JAN) , 1-6. [More Information]
  • Fewings, N., Gatt, P., McKay, F., Parnell, G., Schibeci, S., Edwards, J., Basuki, M., Goldinger, A., Fabis-Pedrini, M., Kermode, A., Burke, T., Vucic, S., Stewart, G., Booth, D., et al (2017). The autoimmune risk gene ZMIZ1 is a vitamin D responsive marker of a molecular phenotype of multiple sclerosis. Journal of Autoimmunity. 78 , 57-69. [More Information]
  • Parnell, G., Booth, D. (2017). The Multiple Sclerosis (MS) genetic risk factors indicate both acquired and innate immune cell subsets contribute to MS pathogenesis and identify novel therapeutic opportunities. Colegio de Farmaceuticos de la Provincia de Buenos Aires. 8 (ARP) , 1-6. [More Information]
  • Read, S., O'Connor, K., Suppiah, V., Ahlenstiel, C., Obeid, S., Cook, K., Cunningham, A., Douglas, M., Hogg, P., Booth, D., George, J., Ahlenstiel, G. (2017). Zinc is a potent and specific inhibitor of IFN-(lambda)3 signaling. Nature Communications. 8 , 1-15. [More Information]
  • Read, S., O'Connor, K., Suppiah, V., Ahlenstiel, C., Obeid, S., Cook, K., Cunningham, A., Douglas, M., Hogg, P., Booth, D., George, J., Ahlenstiel, G. (2017). Zinc is a potent and specific inhibitor of IFN-(lambda)3 signaling. Nature Communications. 8 , 1-15. [More Information]
  • Read, S., O'Connor, K., Suppiah, V., Ahlenstiel, C., Obeid, S., Cook, K., Cunningham, A., Douglas, M., Hogg, P., Booth, D., George, J., Ahlenstiel, G. (2017). Zinc is a potent and specific inhibitor of IFN-/\3 signaling. Nature Communications. 8 , 1-15. [More Information]
  • Read, S., O'Connor, K., Suppiah, V., Ahlenstiel, C., Obeid, S., Cook, K., Cunningham, A., Douglas, M., Hogg, P., Booth, D., George, J., Ahlenstiel, G. (2017). Zinc is a potent and specific inhibitor of IFN-/\3 signaling. Nature Communications. 8 , 1-15. [More Information]
  • Read, S., O'Connor, K., Suppiah, V., Ahlenstiel, C., Obeid, S., Cook, K., Cunningham, A., Douglas, M., Hogg, P., Booth, D., George, J., Ahlenstiel, G. (2017). Zinc is a potent and specific inhibitor of IFNL3 signaling. Nature Communications. 8 , 1-15. [More Information]
  • Read, S., O'Connor, K., Suppiah, V., Ahlenstiel, C., Obeid, S., Cook, K., Cunningham, A., Douglas, M., Hogg, P., Booth, D., George, J., Ahlenstiel, G. (2017). Zinc is a potent and specific inhibitor of IFNL3 signaling. Nature Communications. 8 , 1-15. [More Information]

2016
  • Booth, D., Ding, N., Parnell, G., Shahijanian, F., Coulter, S., Schibeci, S., Atkins, A., Stewart, G., Evans, R., Downes, M., Liddle, C. (2016). Cistromic and genetic evidence that the vitamin D receptor mediates susceptibility to latitude-dependent autoimmune diseases. Genes and Immunity. 17 (4) , 213-219. [More Information]
  • Eslam, M., Mangia, A., Berg, T., Chan, H., Irving, W., Dore, G., Abate, M., Bugianesi, E., Adams, L., Najim, M., Weltman, M., Rahme, A., Booth, D., Liddle, C., Douglas, M., van der Poorten, D., George, J., White, R., Leung, R., et al (2016). Diverse impacts of the rs58542926 E167K variant in TM6SF2 on viral and metabolic liver disease phenotypes. Hepatology. 64 (1) , 34-46. [More Information]
  • Eslam, M., Hashem, A., Romero-Gomez, M., Berg, T., Dore, G., Mangia, A., Chan, H., Irving, W., Sheridan, D., Abate, M., Weltman, M., Kelaeng, K., Ahlenstiel, G., Liddle, C., Douglas, M., Booth, D., George, J., et al (2016). FibroGENE: A gene-based model for staging liver fibrosis. Journal of Hepatology. 64 (2) , 390-398. [More Information]

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  • O'Connor, K., Read, S., Wang, M., Schibeci, S., Eslam, M., Ong, A., Weltman, M., Douglas, M., Mazzola, A., Craxi, A., Stewart, G., Liddle, C., George, J., Ahlenstiel, G., Booth, D., et al (2016). IFNL3/4 genotype is associated with altered immune cell populations in peripheral blood in chronic hepatitis C infection. Genes and Immunity. 17 (6) , 328-334. [More Information]
  • McKay, F., Gatt, P., Fewings, N., Parnell, G., Schibeci, S., Basuki, M., Powell, J., Goldinger, A., Fabis-Pedrini, M., Kermode, A., Burke, T., Vucic, S., Stewart, G., Booth, D. (2016). The low EOMES/TBX21 molecular phenotype in multiple sclerosis reflects CD56+ cell dysregulation and is affected by immunomodulatory therapies. Clinical Immunology. 163 , 96-107. [More Information]
  • Nalos, M., Parnell, G., Robergs, R., Booth, D., McLean, A., Tang, B. (2016). Transcriptional reprogramming of metabolic pathways in critically ill patients. Intensive Care Medicine Experimental. 4 (21) , 1-15. [More Information]
  • Nalos, M., Parnell, G., Robergs, R., Booth, D., McLean, A., Tang, B. (2016). Transcriptional reprogramming of metabolic pathways in critically ill patients. Intensive Care Medicine Experimental. 4 , 1-15. [More Information]

2015
  • Gu, B., Field, J., Dutertre, S., Ou, A., Kilpatrick, T., Lechner-Scott, J., Scott, R., Lea, R., Taylor, B., Stankovich, J., et al (2015). A rare P2X7 variant Arg307Gln with absent pore formation function protects against neuroinflammation in multiple sclerosis. Human Molecular Genetics. 24 (19) , 5644-5654. [More Information]
  • Moutsianas, L., Jostins, L., Beecham, A., Dilthey, A., Xifara, D., Ban, M., Shah, T., Patsopoulos, N., Alfredsson, L., Anderson, C., Booth, D., Stewart, G., et al (2015). Class II HLA interactions modulate genetic risk for multiple sclerosis. Nature Genetics. 47 (10) , 1107-1113. [More Information]
  • Read, S., Tay, E., Shahidi, M., O'Connor, K., Booth, D., George, J., Douglas, M. (2015). Hepatitis C Virus Driven AXL Expression Suppresses the Hepatic Type I Interferon Response. PloS One. 10 (8) , 1-16. [More Information]

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  • Rueger, S., Bochud, P., Dufour, J., Mullhaupt, B., Semela, D., Helm, M., Moradpour, D., Cerny, A., Malinverni, R., Booth, D., Suppiah, V., George, J., et al (2015). Impact of common risk factors of fibrosis progression in chronic hepatitis C. Gut (English Edition): an international journal of gastroenterology and hepatology. 64 (10) , 1605-1615. [More Information]
  • Eslam, M., Hashem, A., Leung, R., Romero-Gomez, M., Berg, T., Dore, G., Chan, H., Irving, W., Sheridan, D., Abate, M., Weltman, M., Douglas, M., Liddle, C., Booth, D., George, J., Ahlenstiel, G., et al (2015). Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease. Nature Communications. 6 , 1-10. [More Information]
  • Mina, M., Luciani, F., Cameron, B., Bull, R., Beard, M., Booth, D., Lloyd, A. (2015). Resistance to hepatitis C virus: potential genetic and immunological determinants. The Lancet Infectious Diseases. 15 (4) , 451-460. [More Information]
  • Field, J., Shahijanian, F., Schibeci, S., Johnson, L., Gresle, M., Laverick, L., Parnell, G., Stewart, G., McKay, F., Kilpatrick, T., Booth, D., et al (2015). The MS Risk Allele of CD40 Is Associated with Reduced Cell-Membrane Bound Expression in Antigen Presenting Cells: Implications for Gene Function.. PloS One. 10 (6) , e0127080. [More Information]

2014
  • Dale, R., Tantsis, E., Merheb, V., Kumaran, R., Sinmaz, N., Pathmanandavel, K., Ramanathan, S., Booth, D., Wienholt, L., Prelog, K., Mathey, E., Brilot-Turville, F., et al (2014). Antibodies to MOG have a demyelination phenotype and affect oligodendrocyte cytoskeleton. Neurology: Neuroimmunology and Neuroinflammation. 2014 (1) , 1-10. [More Information]
  • Ramanathan, S., Reddel, S., Henderson, A., Parratt, J., Barnett, M., Gatt, P., Merheb, V., Kumaran, R., Pathmanandavel, K., Sinmaz, N., Yiannikas, K., Vucic, S., Stewart, G., Booth, D., Dale, R., Brilot-Turville, F., et al (2014). Antibodies to myelin oligodendrocyte glycoprotein in bilateral and recurrent optic neuritis. Neurology: Neuroimmunology and Neuroinflammation. 1 (4) , 1-12. [More Information]
  • O'Connor, K., George, J., Booth, D., Ahlenstiel, G. (2014). Dendritic cells in hepatitis C virus infection: Key players in the IFNL3-genotype response. World Journal of Gastroenterology. 20 (47) , 17830-17838. [More Information]

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  • Roberts, S., Mitchell, J., Leung, R., Booth, D., Bollipo, S., Ostapowicz, G., Sloss, A., McCaughan, G., Dore, G., Thompson, A., George, J., et al (2014). Distribution of interferon lambda-3 gene polymorphisms in Australian patients with previously untreated genotype 1 chronic hepatitis C: Analysis from the PREDICT and CHARIOT studies. Journal of Gastroenterology and Hepatology. 29 (1) , 179-184. [More Information]
  • O'Connor, K., Parnell, G., Patrick, E., Ahlenstiel, G., Suppiah, V., van der Poorten, D., Read, S., Leung, R., Douglas, M., Yang, J., Stewart, G., Liddle, C., George, J., Booth, D. (2014). Hepatic metallothionein expression in chronic hepatitis C virus infection is IFNL3 genotype-dependent. Genes and Immunity. 15 (2) , 88-94. [More Information]
  • O'Connor, K., Ahlenstiel, G., Suppiah, V., Schibeci, S., Ong, A., Leung, R., van der Poorten, D., Douglas, M., Weltman, M., Stewart, G., Liddle, C., George, J., Booth, D. (2014). IFNL3 mediates interaction between innate immune cells: Implications for hepatitis C virus pathogenesis. Innate Immunity. 20 (6) , 598-605. [More Information]
  • Eslam, M., Leung, R., Romero-Gomez, M., Mangia, A., Irving, W., Sheridan, D., Spengler, U., Mollison, L., Cheng, W., Bugianesi, E., Douglas, M., Booth, D., George, J., Ahlenstiel, G., et al (2014). IFNL3 polymorphisms predict response to therapy in chronic hepatitis C genotype 2/3 infection. Journal of Hepatology. 61 (2) , 235-241. [More Information]
  • Parnell, G., Gatt, P., McKay, F., Schibeci, S., Krupa, M., Powell, J., Visscher, P., Montgomery, G., Lechner-Scott, J., Broadley, S., Liddle, C., Vucic, S., Stewart, G., Booth, D., et al (2014). Ribosomal protein S6 mRNA is a biomarker upregulated in multiple sclerosis, downregulated by interferon treatment, and affected by season. Multiple Sclerosis Journal. 20 (6) , 675-685. [More Information]
  • Parnell, G., Gatt, P., Krupa, M., Dorothee, N., McKay, F., Schibeci, S., Batten, M., Baranzini, S., Henderson, A., Barnett, M., Vucic, S., Stewart, G., Booth, D., et al (2014). The autoimmune disease-associated transcription factors EOMES and TBX21 are dysregulated in multiple sclerosis and define a molecular subtype of disease. Clinical Immunology. 151 (1) , 16-24. [More Information]
  • Shahijanian, F., Parnell, G., McKay, F., Gatt, P., Shojaei, M., O'Connor, K., Schibeci, S., Brilot-Turville, F., Liddle, C., Batten, M., Stewart, G., Booth, D. (2014). The CYP27B1 variant associated with increased risk of autoimmune disease is underexpressed in tolerising dendritic cells. Human Molecular Genetics. 23 (6) , 1425-1434. [More Information]
  • Parnell, G., Booth, D. (2014). Whole Blood Transcriptomic Analysis to Identify Clinical Biomarkers of Drug Response. Pharmacogenomics in Drug Discovery and Development. , 35-43.

2013
  • Mechelli, R., Umeton, R., Policano, C., Annibali, V., Coarelli, G., Ricigliano, V., Vittori, D., Fornasiero, A., Buscarinu, M., Booth, D., et al (2013). A "Candidate-Interactome" Aggregate Analysis of Genome-Wide Association Data in Multiple Sclerosis. PloS One. 8 (5) , 1-9. [More Information]
  • Beecham, A., Patsopoulos, N., Xifara, D., Davis, M., Kempinnen, A., Cotsapas, C., Shah, T., Spencer, C., Booth, D., Goris, A., Vucic, S., Stewart, G., et al (2013). Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nature Genetics. 45 (11) , 1353-1362. [More Information]
  • Suppiah, V., Armstrong, N., O'Connor, K., Berg, T., Weltman, M., Abate, M., Spengler, U., Bassendine, M., Dore, G., Irving, W., Stewart, G., George, J., Booth, D., Ahlenstiel, G., et al (2013). CCR5-Delta32 genotype does not improve predictive value of IL28B polymorphisms for treatment response in chronic HCV infection. Genes and Immunity. 14 (5) , 286-290. [More Information]

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  • Mohammad, M., Hassanpour, M., Tsai, V., Li, H., Ruitenberg, M., Booth, D., Serrats, J., Hart, P., Symonds, G., Sawchenko, P., et al (2013). Dendritic cells and multiple sclerosis: disease, tolerance and therapy. International Journal of Molecular Sciences. 14 (1) , 547-562. [More Information]
  • Booth, D. (2013). Do pathogens contribute to multiple sclerosis aetiology?. Microbiology Australia. 2013 , 144-146.
  • Petta, S., Rosso, C., Leung, R., Abate, M., Booth, D., Solomone, F., Gambino, R., Rizzetto, M., Caviglia, P., Smedile, A., George, J., et al (2013). Effects of IL28B rs12979860 CC Genotype on Metabolic Profile and Sustained Virologic Response in Patients with Genotype 1 Chronic Hepatitis C. Clinical Gastroenterology and Hepatology. 11 (3) , 311-317. [More Information]
  • Lee, S., Harold, D., Nyholt, D., Goddard, M., Zondervan, K., Williams, J., Montgomery, G., Wray, N., Visscher, P., Scott, R., Booth, D., Stewart, G., Heard, R., et al (2013). Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis. Human Molecular Genetics. 22 (4) , 832-841. [More Information]
  • Patsopoulos, N., Barcellos, L., Hintzen, R., Schaefer, C., van Duijn, C., Noble, J., Raj, T., Booth, D., Stewart, G., Heard, R., et al (2013). Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: HLA and non-HLA effects. PLoS Genetics. 9 (11) , 1-10. [More Information]
  • Parnell, G., Tang, B., Nalos, M., Armstrong, N., Huang, S., Booth, D., McLean, A. (2013). Identifying key regulatory genes in the whole blood of septic patients to monitor underlying immune dysfunctions. Shock. 40 (3) , 166-174. [More Information]
  • Lin, R., Charlesworth, J., Stankovich, J., Perreau, V., Brown, M., Taylor, B., Baxter, A., Kermode, A., Bahlo, M., Booth, D., Stewart, G., Barnett, M., Heard, R., et al (2013). Identity-by-Descent Mapping to Detect Rare Variants Conferring Susceptibility to Multiple Sclerosis. PloS One. 8 (3) , 1-8. [More Information]
  • McKay, F., Hoe, E., Parnell, G., Gatt, P., Schibeci, S., Stewart, G., Booth, D. (2013). IL7Ralpha Expression and Upregulation by IFNbeta in Dendritic Cell Subsets Is Haplotype-Dependent. PloS One. 8 (10) , 1-10. [More Information]
  • Eslam, M., Booth, D., George, J., Ahlenstiel, G. (2013). Interaction of IFNL3 with insulin resistance, steatosis and lipid metabolism in chronic hepatitis C virus infection. World Journal of Gastroenterology. 19 (41) , 7055-7061. [More Information]
  • Booth, D., George, J. (2013). Loss of function of the new interferon IFN-λ4 may confer protection from hepatitis C. Nature Genetics. 45 (2) , 119-120. [More Information]
  • Lill, C., Schjeide, B., Graetz, C., Ban, M., Alcina, A., Ortiz, M., Perez, J., Damotte, V., Booth, D., de Lapuente, A., Stewart, G., et al (2013). MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis. Brain. 136 (6) , 1778-1782. [More Information]
  • Baranzini, S., Khankhanian, P., Patsopoulos, N., Li, M., Stankovich, J., Cotsapas, C., Bach Søndergaard, H., Ban, M., Booth, D., Stewart, G., et al (2013). Network-Based Multiple Sclerosis Pathway Analysis with GWAS Data from 15,000 Cases and 30,000 Controls. American Journal of Human Genetics. 92 , 854-865. [More Information]
  • Mero, I., Gustavsen, M., Sæther, H., Fla ̊ m, S., Berg-Hansen, P., Søndergaard, H., Jensen, P., Berge, T., Bjølgerud, A., et al, V., et al (2013). Oligoclonal Band Status in Scandinavian Multiple Sclerosis Patients Is Associated with Specific Genetic Risk Alleles. PloS One. 8 (3) , e58352-e58352. [More Information]
  • Cortes, A., Field, J., Glazov, E., Hadler, J., Stankovich, J., Brown, M., Baxter, A., Kermode, A., Taylor, B., Booth, D., Stewart, G., Vucic, S., et al (2013). Resequencing and fine-mapping of the chromosome 12q13-14 locus associated with multiple sclerosis refines the number of implicated genes. Human Molecular Genetics. 22 (11) , 2283-2292. [More Information]

2012
  • Parnell, G., McLean, A., Booth, D., Armstrong, N., Nalos, M., Huang, S., Manak, J., Tang, W., Tam, O., Chan, S., Tang, B. (2012). A distinct influenza infection signature in the blood transcriptome of patients with severe community-acquired pneumonia. Critical Care. 16 (4) , 1-12. [More Information]
  • Martinelli-Boneschi, F., Esposito, F., Brambilla, P., Lindstrom, E., Lavorgna, G., Stankovich, J., Rodegher, M., Capra, R., Ghezzi, A., Coniglio, G., Booth, D., Stewart, G., et al (2012). A genome-wide association study in progressive multiple sclerosis. Multiple Sclerosis Journal. 18 (10) , 1384-1394. [More Information]
  • Fischer, J., Bohm, S., Scholz, M., Muller, T., Witt, H., George, J., Sarrazin, C., Susser, S., Schott, E., Suppiah, V., Booth, D., Stewart, G., et al (2012). Combined effects of different interleukin-28B gene variants on the outcome of dual combination therapy in chronic hepatitis C virus type 1 infection. Hepatology. 55 (6) , 1700-1710. [More Information]

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  • Patin, E., Kutalik, Z., Guergnon, J., Bibert, S., Nalpas, B., Jouanguy, E., Munteanu, M., Bousquet, L., Argiro, L., Halfon, P., Suppiah, V., Stewart, G., Booth, D., George, J., et al (2012). Genome-Wide Association Study Identifies Variants Associated With Progression of Liver Fibrosis From HCV Infection. Gastroenterology. 143 (5) , 1244-1252. [More Information]
  • Booth, D., Ahlenstiel, G., George, J. (2012). Pharmacogenomics of hepatitis C infections: personalizing therapy. Genome Medicine. 4 (12) , 1-10. [More Information]
  • Rajasuriar, R., Booth, D., Gouillou, M., Spelman, T., James, I., Solomon, A., Chua, K., Stewart, G., Deeks, S., Bangsberg, D., et al (2012). The role of SNPs in the α-chain of the IL-7R gene in CD4+ T-cell recovery in HIV-infected African patients receiving suppressive cART. Genes and Immunity. 13 (1) , 83-93. [More Information]
  • Suan, D., Booth, D., Kennedy, I., Downie, J., Earls, P., Gottlieb, D., Stewart, G., Ling, M. (2012). Vitreal deposits in Val71Ala transthyretin amyloidosis. Internal Medicine Journal. 42 (1) , 106-108. [More Information]
  • Ahlenstiel, G., Booth, D., George, J. (2012). Will IL28B polymorphisms remain relevant to direct-acting antiviral treatment paradigms?. Antiviral Therapy. 17 (6 Pt B) , 1163-1170. [More Information]

2011
  • Parnell, G., McLean, A., Booth, D., Huang, S., Nalos, M., Tang, B. (2011). Aberrant Cell Cycle and Apoptotic Changes Characterise Severe Influenza A Infection - A Meta-Analysis of Genomic Signatures in Circulating Leukocytes. PloS One. 6 (3) , e17186-1-e17186-10. [More Information]
  • Ahlenstiel, G., Booth, D., George, J. (2011). Clinical significance of IL28B gene variation in hepatitis C virus infection. Hot Topics in viral Hepatitis. (20) , 17-24. [More Information]
  • Sawcer, S., Hallenthal, G., Pirinen, M., Spencer, C., Patsopoulos, N., Moutsianas, L., Dilthey, A., Su, Z., et al, V., Booth, D., Heard, R., Stewart, G. (2011). Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature. 476 (7359) , 214-219. [More Information]

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  • Patsopoulos, N., Esposito, F., Reischl, J., Lehr, S., Bauer, D., Heubach, J., Sandbrink, R., Pohl, C., Edan, G., Kappos, L., Booth, D., et al (2011). Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Annals of Neurology. 70 (6) , 897-912. [More Information]
  • Afdhal, N., McHutchison, J., Zeuzem, S., Mangia, A., Pawlotsky, J., Murray, J., Shianna, K., Tanaka, Y., Thomas, D., Booth, D., et al (2011). Hepatitis C Pharmacogenetics: State of the Art in 2010. Hepatology. 53 (1) , 336-345. [More Information]
  • Smith, K., Suppiah, V., O'Connor, K., Berg, T., Weltman, M., Abate, M., Spengler, U., Bassendine, M., Matthews, G., Irving, W., Ahlenstiel, G., Stewart, G., George, J., Booth, D., et al (2011). Identification of improved IL28B SNPs and haplotypes for prediction of drug response in treatment of hepatitis C using massively parallel sequencing in a cross-sectional European cohort. Genome Medicine. 3 (8) , 57-1-57-13. [More Information]
  • Suppiah, V., Gaudieri, S., Armstrong, N., O'Connor, K., Berg, T., Weltman, M., Abate, M., Spengler, U., Bassendine, M., Dore, G., Ahlenstiel, G., Stewart, G., George, J., Booth, D., et al (2011). IL28B, HLA-C, and KIR Variants Additively Predict Response to Therapy in Chronic Hepatitis C Virus Infection in a European Cohort: A Cross-Sectional Study.. PLoS Medicine. 8 (9) , e1001092-1-e1001092-8. [More Information]
  • Cunningham, A., Booth, D. (2011). The first common cold sore susceptibility gene. The Journal of Infectious Diseases. 204 (11) , 1645-1647. [More Information]
  • Suan, D., O'Connor, K., Booth, D., Liddle, C., Stewart, G. (2011). Voriconazole toxicity related to polymorphisms in CYP2C19. Internal Medicine Journal. 41 (4) , 364-365. [More Information]

2010
  • Field, J., Browning, S., Johnson, L., Danoy, P., Varney, M., Tait, B., Gandhi, K., Charlesworth, J., Heard, R., The Australia and New Zealand Multiple Sclerosis Genetics Consortium, (., Stewart, G., Booth, D., et al (2010). A Polymorphism in the HLA-DPB1 Gene Is Associated with Susceptibility to Multiple Sclerosis. PloS One. 5 (10) , 1-7. [More Information]
  • Riveros, C., Mellor, D., Gandhi, K., McKay, F., Cox, M., Berretta, R., Vaezpour, S., Inostroza-Ponta, M., Broadley, S., Heard, R., Vucic, S., Stewart, G., Booth, D., et al (2010). A Transcription Factor Map as Revealed by a Genome-Wide Gene Expression Analysis of Whole-Blood mRNA Transcriptome in Multiple Sclerosis. PloS One. 5 (12) , e14176-1-e14176-28. [More Information]
  • Rajasuriar, R., Booth, D., Solomon, A., Chua, K., Spelman, T., Gouillou, M., Schlub, T., Davenport, M., Crowe, S., Elliot, J., Stewart, G., et al (2010). Biological Determinants of Immune Reconstitution in HIV-Infected Patients Receiving Antiretroviral Therapy: The Role of Interleukin 7 and Interleukin 7 Receptor alpha and Microbial Translocation. The Journal of Infectious Diseases. 202 (8) , 1254-1264. [More Information]

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  • Hoe, E., McKay, F., Schibeci, S., Gandhi, K., Heard, R., Stewart, G., Booth, D. (2010). Functionally significant differences in expression of disease-associated IL-7 receptor alpha haplotypes in CD4 T cells and dendritic cells. The Journal of Immunology. 184 (5) , 2512-2517. [More Information]
  • Esposito, F., Patsopolous, N., Cepok, S., Kockum, J., Leppa, V., Booth, D., Heard, R., Stewart, G., Cox, M., Scott, R., et al (2010). IL12A, MPHOSPH9/CDK2AP1 and RGS1 are novel multiple sclerosis susceptibility loci. Genes and Immunity. 11 (5) , 397-405. [More Information]
  • Ahlenstiel, G., Booth, D., George, J. (2010). IL28B in hepatitis C virus infection: translating pharmacogenomics into clinical practice. Journal of Gastroenterology and Hepatology. 45 (9) , 903-910. [More Information]
  • Hoe, E., McKay, F., Schibeci, S., Heard, R., Stewart, G., Booth, D. (2010). Interleukin 7 Receptor Alpha Chain (IL-7Ralpha) Haplotypes Vary in Their Influence on Multiple Sclerosis Susceptibility and Response to Interferon Beta. Journal of Interferon and Cytokine Research. 30 (5) , 291-298. [More Information]
  • Booth, D., Heard, R., Stewart, G., Cox, M., Scott, R., Lechner-Scott, J., Goris, A., Dobosi, R., Dubois, B., Saarela, J., et al (2010). Lack of support for association between the KIF1B rs10492972[C] variant and multiple sclerosis. Nature Genetics. 42 (6) , 469-470. [More Information]
  • Cox, M., Cairns, M., Gandhi, K., Carroll, A., Moscovis, S., Stewart, G., Broadley, S., Scott, R., Booth, D., Lechner-Scott, J., et al (2010). MicroRNAs miR-17 and miR-20a Inhibit T Cell Activation Genes and Are Under-Expressed in MS Whole Blood. PloS One. 5 (8) , e12132 - 1-e12132 - 7. [More Information]
  • Gandhi, K., McKay, F., Diefenbach, E., Crossett, B., Schibeci, S., Heard, R., Stewart, G., Booth, D., Arthur, J. (2010). Novel approaches to detect serum biomarkers for clinical response to interferon-beta treatment in multiple sclerosis. PloS One. 5 (5) , e10484 - 1-e10484 - 9. [More Information]
  • Grebely, J., Petoumenos, K., Hellard, M., Matthews, G., Suppiah, V., Applegate, T., Yeung, B., Marks, P., Rawlinson, W., Lloyd, A., Booth, D., George, J., et al (2010). Potential Role for Interleukin-28B Genotype in Treatment Decision-Making in Recent Hepatitis C Virus Infection. Hepatology. 52 (4) , 1216-1224. [More Information]
  • Gandhi, K., McKay, F., Cox, M., Riveros, C., Armstrong, N., Heard, R., Vucic, S., Williams, D., Stankovich, J., Brown, M., Stewart, G., Booth, D., et al (2010). The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis. Human Molecular Genetics. 19 (11) , 2134-2143. [More Information]

2009
  • Booth, D. (2009). An 82-year-old woman with intermittent claudication. Medicine Today. 10 (4) , 72-73.
  • Bahlo, M., Booth, D., Broadley, S., Brown, M., Foote, S., Griffiths, L., Kilpatrick, T., Lechner-Scott, J., Moscato, P., Perreau, V., Stewart, G., Wiley, J., et al (2009). Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. Nature Genetics. 41 (7) , 824-830. [More Information]
  • Suppiah, V., Moldovan, M., Ahlenstiel, G., Berg, T., Weltman, M., Abate, M., Bassendine, M., Spengler, U., Dore, G., Powell, E., Stewart, G., Booth, D., George, J., et al (2009). IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy.. Nature Genetics. 41 (10) , 1100-1104. [More Information]

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  • Ban, M., Goris, A., Lorentzen, A., Baker, A., Mihalova, T., Ingram, G., Booth, D., Heard, R., Stewart, G., Bogaert, E., et al (2009). Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor. European Journal of Human Genetics. 17 , 1309-1313. [More Information]
  • De Jager, P., Baecher-Allan, C., Maier, L., Arthur, A., Ottoboni, L., Barcellos, L., McCauley, J., Sawcer, S., Goris, A., Saarela, J., Booth, D., Stewart, G., et al (2009). The role of the CD58 locus in multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 106 (13) , 5264-5269. [More Information]

2008
  • Gandhi, K., McKay, F., Schibeci, S., Arthur, J., Heard, R., Stewart, G., Booth, D. (2008). BAFF is a Biological Response Marker to IFN-beta Treatment in Multiple Sclerosis. Journal of Interferon and Cytokine Research. 28 (9) , 529-540. [More Information]
  • McKay, F., Swain, L., Schibeci, S., Rubio, J., Kilpatrick, T., Heard, R., Stewart, G., Booth, D. (2008). CD127 immunophenotyping suggests altered CD4(+) T cell regulation in primary progressive multiple sclerosis. Journal of Autoimmunity. 31 (1) , 52-58. [More Information]
  • Arthur, A., Armati, P., Bye, C., The Southern MS Genetics Consortium, N., Heard, R., Stewart, G., Pollard, J., Booth, D. (2008). Genes implicated in multiple sclerosis pathogenesis from consilience of genotyping and expression profiles in relapse and remission. BMC Medical Genetics. 9 (17) , 1-12. [More Information]

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  • Burfoot, R., Jensen, C., Field, J., Stankovich, J., Varney, M., Johnson, L., Butzkueven, H., Booth, D., Bahlo, M., Tait, B., Heard, R., Stewart, G., et al (2008). SNP mapping and candidate gene sequencing in the class I region of the HLA complex: searching for multiple sclerosis susceptibility genes in Tasmanians. Tissue Antigens: immune response genetics. 71 (1) , 42-50. [More Information]

2007
  • Hensiek, A., Seaman, S., Barcellos, L., Oturai, A., Eraksoi, M., Cocco, E., Vecsei, L., Stewart, G., Dubois, B., Bellman-Strobl, J., Booth, D., et al (2007). Familial effects on the clinical course of multiple sclerosis. Neurology. 68 (5) , 376-383.
  • McKay, F., Swain, L., Schibeci, S., Rubio, J., Kilpatrick, T., Heard, R., Stewart, G., Booth, D. (2007). Haplotypes of the interleukin 7 receptor alpha gene are correlated with altered expression in whole blood cells in multiple sclerosis. Genes and Immunity. 9 ((accepted 6 September, 2007)) , 1-6.

2006
  • Bugeja, M., Booth, D., Bennetts, B., Heard, R., Rubio, J., Stewart, G. (2006). An investigation of polymorphisms in the 17q11.2-12 CC chemokine gene cluster for association with multiple sclerosis in Australians.. BMC Medical Genetics. 7 , 64-64.
  • Bugeja, M., Booth, D., Bennetts, B., Heard, R., Stewart, G. (2006). An investigation of polymorphisms in the 4q1 3.3-21.1 CXC chemokine gene cluster for association with multiple sclerosis in Australians.. Multiple Sclerosis: clinical and laboratory research. 12 (6) , 710-722.
  • McKay, F., Schibeci, S., Heard, R., Stewart, G., Booth, D. (2006). Analysis of neutralizing antibodies to therapeutic interferon-beta in multiple sclerosis patients: a comparison of three methods in a large Australasian cohort.. Journal of Immunological Methods. 310 (1-2) , 20-29. [More Information]

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  • Lachmann, J., Sengul, B., Yavuzsen, T., Booth, D., Booth, S., Bybee, A., Gallimore, J., Soyturk, M., Akar, S., Tunca, M., et al (2006). Clinical and subclinical inflammation in patients with familial Mediterranean fever and in heterozygous carriers of MEFV mutations.. Rheumatology (Print Edition). 45 (6) , 746-750. [More Information]

2005
  • Sawcer, S., Ban, M., Maranian, M., Yeo, T., Compston, A., Kirby, A., Daly, M., De Jager, P., Walsh, E., Heard, R., Stewart, G., Booth, D., et al (2005). A high-density screen for linkage in multiple sclerosis. The American Journal of Human Genetics. 77 (3) , 454-467. [More Information]
  • Sawcer, S., Ban, M., Maranian, M., Yeo, T., Compston, A., Kirby, A., Daly, M., De Jager, P., Walsh, E., Heard, R., Stewart, G., Booth, D., et al (2005). A high-density screen for linkage in multiple sclerosis.. American Journal of Human Genetics.
  • Bugeja, M., Booth, D., Bennetts, B., Heard, R., Burgner, D., Stewart, G. (2005). An investigation of NOS2A promoter polymorphisms in Australian multiple sclerosis patients.. European Journal of Human Genetics. 13 (7) , 815-822.

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  • Booth, D., Arthur, A., Teutsch, S., Bye, C., Rubio, J., Armati, P., Pollard, J., Heard, R., Stewart, G. (2005). Gene expression and genotyping studies implicate the interleukin 7 receptor in the pathogenesis of primary progressive multiple sclerosis. Journal of Molecular Medicine.

2004
  • Bugeja, M., Booth, D., Bennetts, B., Guerin, J., Kaldor, J., Stewart, G. (2004). Analysis Of The Ccl3-L1 Gene For Association With Hiv-1 Susceptibility And Disease Progression.. AIDS. 18 (7) , 1069-1071.
  • Teutsch, S., Booth, D., Bennetts, B., Heard, R., Stewart, G. (2004). Association Of Common T Cell Activation Gene Polymorphisms With Multiple Sclerosis In Australian Patients.. Journal of Neuroimmunology. 148 (2) , 218-30. [More Information]

2003
  • Ban, M., Sawcer, S., Heard, R., Bennetts, B., Adams, S., Booth, D., Perich, V., Setakis, E., Compston, A., Stewart, G. (2003). A genome-wide screen for linkage disequilibrium in Australian HLA-DRB1*1501 positive multiple sclerosis patients. Journal of Neuroimmunology. 143 (1-2) , 60-64. [More Information]
  • Teutsch, S., Booth, D., Bennetts, B., Heard, R., Stewart, G. (2003). Identification of 11 novel and common single nucleotide polymorphisms in the interleukin-7 receptor-alpha gene and their associations with multiple sclerosis. European Journal of Human Genetics. 11 (7) , 509-515.
  • Esposito, G., Garcia, J., Mangione, P., Giorgetti, S., Corazza, A., Viglino, P., Chiti, F., Andreola, A., Dumy, P., Booth, D., et al (2003). Structural and folding dynamic properties of the T70N variant of human lysozyme. Journal of Biological Chemistry. 278 (28) , 25910-25918.