Publications

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2017
  • Carlessi, R., Chen, Y., Rowlands, J., Cruzat, V., Keane, K., Egan, L., Mamotte, C., Stokes, R., Gunton, J., de Bittencourt, P., et al (2017). GLP-1 receptor signalling promotes ?-cell glucose metabolism via mTOR-dependent HIF-1? activation. Scientific Reports. 7 (1) , 1-13. [More Information]
  • Stokes, R., Cheng, K., Lalwani, A., Swarbrick, M., Thomas, H., Loudovaris, T., Kay, T., Hawthorne, W., O'Connell, P., Gunton, J. (2017). Transplantation sites for human and murine islets. Diabetologia. 60 (10) , 1961-1971. [More Information]
  • Stokes, R., Simond, D., Burns, H., Patel, A., O'Connell, P., Gunton, J., Hawthorne, W. (2017). Transplantation sites for porcine islets. Diabetologia. 60 (10) , 1972-1976. [More Information]

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  • Christie-David, D., Gunton, J. (2017). Vitamin C deficiency and diabetes mellitus � easily missed?. Diabetic Medicine. 34 (2) , 294-296. [More Information]
  • Elangovan, H., Chahal, S., Gunton, J. (2017). Vitamin D in liver disease: Current evidence and potential directions. Biochimica et Biophysica Acta-Molecular Basis of Disease. 1863 (4) , 907-916. [More Information]
  • Christensen, J., Cheng, J., Earls, P., Gunton, J., Sewell, W., Sacks, R., Harvey, R. (2017). Vitamin D pathway regulatory genes encoding 1α-hydroxylase and 24-hydroxylase are dysregulated in sinonasal tissue during chronic rhinosinusitis. International Forum of Allergy & Rhinology. 7 (2) , 169-176. [More Information]

2016
  • Gunton, J., Gates, F., Fulcher, G., Clifton-Bligh, P. (2016). Bone Mineral Density in Postmenopausal Women Heterozygous for the C282Y HFE Mutation. Journal of Osteoporosis. 2016 , 1-6. [More Information]
  • Do, H., Gunton, J., Gaisano, H., Thorn, P. (2016). Changes in beta cell function occur in prediabetes and early disease in the Lepr (db) mouse model of diabetes. Diabetologia. 59 (6) , 1222-1230. [More Information]
  • Do, H., Gunton, J., Gaisano, H., Thorn, P. (2016). Changes in beta cell function occur in prediabetes and early disease in the Leprdb mouse model of diabetes. Diabetologia. 59 (6) , 1222-1230. [More Information]

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  • Burns, K., Christie-David, D., Gunton, J. (2016). Fluconazole in the treatment of Cushing's disease. Endocrinology, Diabetes & Metabolism Case Reports. 2016 , 1-5. [More Information]
  • Bensellam, M., Maxwell, E., Chan, J., Luzuriaga, J., West, P., Jonas, J., Gunton, J., Laybutt, D. (2016). Hypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cells. Diabetologia. 59 (7) , 1492-1502. [More Information]

2015
  • Lam, T., Burns, K., Dennis, M., Cheung, N., Gunton, J. (2015). Assessment of cardiovascular risk in diabetes: Risk scores and provocative testing. World Journal of Diabetes. 6 (4) , 634-641. [More Information]
  • Gunton, J., Girgis, C., Baldock, P., Lips, P. (2015). Bone muscle interactions and vitamin D. Bone. 80 , 89-94. [More Information]
  • Scott, C., Cha, K., Rao, R., Liddle, C., George, J., Gunton, J. (2015). Hepatocyte- Specific Deletion of ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator) Results in Altered Fibrotic Gene Expression in the Thioacetamide Model of Liver Injury. PloS One. 10 (3) , 1-11. [More Information]

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  • Yeap, B., Divitini, M., Gunton, J., Olynyk, J., Beilby, J., McQuillan, B., Hung, J., Knuiman, M. (2015). Higher ferritin levels, but not serum iron or transferrin saturation, are associated with Type 2 diabetes mellitus in adult men and women free of genetic haemochromatosis. Clinical Endocrinology. 82 (4) , 525-532. [More Information]
  • Hocking, S., Stewart, R., Brandon, A., Suryana, E., Stuart, E., Baldwin, E., Kolumam, G., Modrusan, Z., Junutula, J., Gunton, J., James, D., et al (2015). Subcutaneous fat transplantation alleviates diet-induced glucose intolerance and inflammation in mice. Diabetologia. 58 (7) , 1587-1600. [More Information]
  • Downes, M., Bettington, E., Gunton, J., Turkstra, E. (2015). Triple therapy in type 2 diabetes; A systematic review and network meta-analysis. PeerJ. 2015 (12) , 1-21. [More Information]
  • Girgis, C., Cha, K., Houweling, P., Rao, R., Mokbel, N., Lin, M., Clifton-Bligh, R., Gunton, J. (2015). Vitamin D Receptor Ablation and Vitamin D Deficiency Result in Reduced Grip Strength, Altered Muscle Fibers, and Increased Myostatin in Mice. Calcified Tissue International. 97 (6) , 602-610. [More Information]

2014
  • Greenwood, N., Gunton, J. (2014). A computational proof of concept of a machine-intelligent artificial pancreas using lyapunov stability and differential game theory. Journal of Diabetes Science and Technology. 8 (4) , 791-806. [More Information]
  • Gunton, J., Cheung, N., Davis, T., Zoungas, S., Colagiuri, S. (2014). A new blood glucose management algorithm for type 2 diabetes. Medical Journal of Australia. 201 (11) , 650-653. [More Information]
  • Lalwani, A., Stokes, R., Lau, S., Gunton, J. (2014). Deletion of ARNT (Aryl hydrocarbon receptor nuclear translocator) in β-cells causes islet transplant failure with impaired β-cell function. PloS One. 9 (5) , e98435. [More Information]

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  • Girgis, C., Clifton-Bligh, R., Turner, N., Lau, S., Gunton, J. (2014). Effects of Vitamin D in Skeletal Muscle: Falls, Strength, Athletic Performance and Insulin Sensitivity. Clinical Endocrinology. 80 (2) , 169-181. [More Information]
  • Scott, C., Bonner, J., Min, D., Boughton, P., Stokes, R., Cha, K., Walters, S., Masolowski, K., Sierro, F., Grey, S., Twigg, S., McLennan, S., Gunton, J. (2014). Reduction of ARNT in myeloid cells causes immune suppression and delayed wound healing. American Journal of Physiology: Cell Physiology. 307 (4) , C349-C357. [More Information]
  • Girgis, C., Mokbel, N., Cha, K., Houweling, P., Abboud, M., Fraser, D., Mason, R., Clifton-Bligh, R., Gunton, J. (2014). The Vitamin D receptor (VDR) is Expressed in Skeletal Muscle of Male Mice and Modulates 25- Hydroxyvitamin D (25OHD) Uptake in myofibres. Endocrinology. 155 (9) , 3227-3237. [More Information]
  • Sherman, M., Yu, R., Engle, D., Ding, N., Atkins, A., Tiriac, H., Collisson, E., Connor, F., Van Dyke, T., Kozlov, S., Lau, S., Gunton, J., Liddle, C., et al (2014). Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy. Cell. 159 (1) , 80-93. [More Information]
  • Girgis, C., Clifton-Bligh, R., Mokbel, N., Cheng, K., Gunton, J. (2014). Vitamin D Signaling Regulates Proliferation, Differentiation and Myotube Size in C2C12 Skeletal Muscle Cells. Endocrinology. 155 (2) , 347-357. [More Information]
  • Yap, C., Cheung, N., Gunton, J., Athayde, N., Munns, C., Duke, A., Mclean, M. (2014). Vitamin D Supplementation and the Effects on Glucose Metabolism During Pregnancy: A Randomized Controlled Trial. Diabetes Care. 37 (7) , 1837-1844. [More Information]

2013
  • Ding, N., Yu, R., Subramaniam, N., Sherman, M., Wilson, C., Rao, R., Leblanc, M., Coulter, S., He, M., Scott, C., Liddle, C., et al (2013). A Vitamin D Receptor/SMAD Genomic Circuit Gates Hepatic Fibrotic Response. Cell. 153 (3) , 601-613. [More Information]
  • Lau, S., Cha, K., Karunatillake, A., Stokes, R., Cheng, K., Mclean, M., Cheung, N., Gonzalez, F., Gunton, J. (2013). Beta-Cell ARNT Is Required for Normal Glucose Tolerance in Murine Pregnancy. PloS One. 8 (10) , 1-9. [More Information]
  • Stokes, R., Cheng, K., Deters, N., Lau, S., Hawthorne, W., O'Connell, P., Stolp, J., Grey, S., Loudovaris, T., Kay, T., Gunton, J., et al (2013). Hypoxia-inducible factor-1α (HIF-1α) potentiates β-cell survival after islet transplantation of human and mouse islets. Cell Transplantation. 22 (2) , 253-266. [More Information]

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  • O'Connell, P., Holmes-Walker, J., Goodman, D., Hawthorne, W., Loudovaris, T., Gunton, J., Thomas, H., Grey, S., Drogemuller, C., Ward, G., et al (2013). Multicenter Australian Trial of Islet Transplantation: Improving Accessibility and Outcomes. American Journal of Transplantation. 13 (7) , 1850-1858. [More Information]
  • Girgis, C., Clifton-Bligh, R., Hamrick, M., Holick, M., Gunton, J. (2013). The Roles of Vitamin D in Skeletal Muscle: Form, Function, and Metabolism. Endocrine Reviews. 34 (1) , 33-83. [More Information]

2012
  • Cheng, K., Delghingaro-Augusto, V., Nolan, C., Turner, N., Hallahan, N., Andrikopoulos, S., Gunton, J. (2012). High Passage MIN6 Cells Have Impaired Insulin Secretion with Impaired Glucose and Lipid Oxidation. PloS One. 7 (7) , 1-12. [More Information]
  • Cowley, M., Weinberg, A., Zammit, N., Walters, S., Hawthorne, W., Loudovaris, T., Thomas, H., Kay, T., Gunton, J., Alexander, S., O'Connell, P., et al (2012). Human islets express a marked proinflammatory molecular signature prior to transplantation. Cell Transplantation. 21 (9) , 2063-2078. [More Information]
  • Gunton, J., Sisavanh, M., Stokes, R., Satin, J., Satin, L., Zhang, M., Liu, S., Cai, W., Cheng, K., Cooney, G., et al (2012). Mice Deficient in GEM GTPase Show Abnormal Glucose Homeostasis Due to Defects in Beta-Cell Calcium Handling. PloS One. 7 (6) , 1-9. [More Information]

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  • Girgis, C., Cheng, K., Scott, C., Gunton, J. (2012). Novel links between HIFs, type 2 diabetes, and metabolic syndrome. Trends in Endocrinology and Metabolism. 23 (8) , 372-380. [More Information]
  • Girgis, C., Cheng, K., Scott, C., Gunton, J. (2012). Novel links between HIFs, type 2 diabetes, and metabolic syndrome.. Trends in Endocrinology and Metabolism. 23 (8) , 372-380. [More Information]
  • Gunton, J., Girgis, C. (2012). Pancreatic beta-cell failure in the pathogenesis of type 2 diabetes. A Modern Epidemic: Expert Perspectives on Obesity and Diabetes. , 87-104.
  • Girgis, C., Gunton, J., Cheung, N. (2012). The Influence of Ethnicity on the Development of Type 2 Diabetes Mellitus in Women with Gestational Diabetes: A Prospective Study and Review of the Literature. ISRN Endocrinology. 2012 , 1-7. [More Information]

2011
  • Folli, F., Okada, T., Perego, C., Gunton, J., Liew, C., Akiyama, M., D'Amico, A., La Rosa, S., Placidi, C., Lupi, R., et al (2011). Altered insulin receptor signalling and β-cell cycle dynamics in type 2 diabetes mellitus. PloS One. 8 (11) , e28050-e28050. [More Information]
  • Deters, N., Stokes, R., Gunton, J. (2011). Islet transplantation: factors in short-term islet survival. Archivum Immunologiae Et Therapiae Experimentalis. 59 (6) , 421-429. [More Information]
  • Lau, S., Gunton, J., Athayde, N., Byth Wilson, K., Cheung, N. (2011). Serum 25-hydroxyvitamin D and glycated haemoglobin levels in women with gestational diabetes mellitus. Medical Journal of Australia. 194 (7) , 334-337.

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  • Lau, S., Lin, S., Stokes, R., Cheng, K., Baldock, P., Enriquez, R., Mclean, M., Cheung, N., Sainsbury, A., Gonzalez, F., Gunton, J., et al (2011). Synergistic effects of genetic beta cell dysfunction and maternal glucose intolerance on offspring metabolic phenotype in mice. Diabetologia. 54 (4) , 910-921. [More Information]

2010
  • Cheng, K., Ho, K., Stokes, R., Scott, C., Lau, S., Hawthorne, W., O'Connell, P., Loudovaris, T., Kay, T., Kulkarni, R., Biankin, A., Kench, J., Gunton, J., et al (2010). Hypoxia-inducible factor-1alpha regulates beta cell function in mouse and human islets. Journal of Clinical Investigation. 120 (6) , 2171-2183. [More Information]

2008
  • Kebede, M., Favaloro, J., Gunton, J., Laybutt, D., Shaw, M., Wong, N., Fam, B., Aston-Mourney, K., Rantzau, C., Zulli, A., et al (2008). Fructose-1,6-bisphosphatase overexpression in pancreatic beta-cells results in reduced insulin secretion: a new mechanism for fat-induced impairment of beta-cell function. Diabetes. 57 (7) , 1887-1895. [More Information]

2004
  • Chan, S., Nery, L., McElduff, A., Wilmshurst, E., Fulcher, G., Robinson, B., Stiel, J., Gunton, J., Clifton-Bligh, P. (2004). Intravenous Pamidronate In The Treatment And Prevention Of Osteoporosis.. Internal Medicine Journal. 34 (4) , 162-166.

2003
  • Gunton, J., Delhanty, P., Takahashi, S., Baxter, R. (2003). Metaformin rapidly increases insulin receptor activation in human liver and signals preferentially through insulin-receptor substrate-2. Journal of Clinical Endocrinology and Metabolism. 88 (3) , 1323-1332.

2002
  • McElduff, A., McElduff, P., Gunton, J., Hams, G., Wiley, V., Wilcken, B. (2002). Neonatal thyroid-stimulating hormone concentrations in northern Sydney: further indications of mild iodine deficiency. Medical Journal of Australia. 176 (7) , 317-320.

2000
  • Gunton, J., McElduff, A., Sulway, M., Stiel, J., Kelso, I., Boyce, S., Fulcher, G., Robinson, B., Clifton-Bligh, P., Wilmshurst, E. (2000). Outcome of pregnancies complicated by pre-gestational diabetes mellitus. American Journal of Obstetrics & Gynecology. 40 , 38-43.