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  • Liuwantara, D., Chew, Y., Favaloro, E., Hawkes, J., Burns, H., O'Connell, P., Hawthorne, W. (2016). Characterizing the mechanistic pathways of the instant blood-mediated inflammatory reaction in xenogeneic neonatal islet cell transplantation. Transplantation Direct. 2 (6) , 1-10. [More Information]
  • Joglekar, M., Trivedi, P., Kay, T., Hawthorne, W., O'Connell, P., Jenkins, A., Hardikar, A., Thomas, H. (2016). Human islet cells are killed by BID-independent mechanisms in response to FAS ligand. Apoptosis. 21 (4) , 379-389. [More Information]

  • Stewart, J., Tarantal, A., Hawthorne, W., Salvaris, E., O'Connell, P., Nottle, M., D'Apice, A., Cowan, P., Kearns-Jonker, M. (2015). Clonidine inhibits anti-non-Gal IgM xenoantibody elicited in multiple pig-to-primate models. Xenotransplantation. 22 (6) , 413-426. [More Information]
  • Kim, H., Hawthorne, W. J., Kang, H. J., Lee, Y. J., Hwang, J.-I., Hurh, S., Ro, H., Jeong, J. C., Cho, B., Yang, J. and Ahn, C. (2015). Human thrombomodulin regulates complement activation as well as the coagulation cascade in xeno-immune response. Xenotransplantation. 4 (22) , 260-272.
  • Marathe, C., Drogemuller, C., Marathe, J., Loudavaris, T., Hawthorne, W., O'Connell, P., Radford, T., Kay, T., Horowitz, M., Coates, P., et al (2015). Islet Cell Transplantation in Australia: Screening, Remote Transplantation, and Incretin Hormone Secretion in Insulin Independent Patients. Hormone And Metabolic Research. 47 (1) , 16-23. [More Information]

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  • Jimenez, E., Davies, S., Phillips, P., O'Connell, P., Hawthorne, W. (2015). Long-term cultured neonatal islet cell clusters demonstrate better outcomes for reversal of diabetes: In vivo and molecular profiles. Xenotransplantation. 22 (2) , 114-123. [More Information]
  • Chung, H., Lam, V., Yuen, L., Ryan, B., O'Connell, P., Chapman, J., Hawthorne, W., Pleass, H. (2015). Renal transplantation: better fat than thin. Journal of Surgical Research. 194 (2) , 644-652. [More Information]
  • Tran, H., Tran, K., Turingan, I., Zajkowska, M., Lam, V. and Hawthorne, W. (2015). Single-incision laparoscopic inguinal herniorraphy with telescopic extraperitoneal dissection: technical aspects and potential benefits. Hernia. 3 (19) , 407-416.
  • Tran, H., Tran, K., Zajkowska, M., Lam, V. and Hawthorne, W. J. (2015). Single-Incision Laparoscopic Repair of Spigelian Hernia. Jsls-Journal of the Society of Laparoendoscopic Surgeons. 1 (19)
  • Tran, H., Tran, K., Zajkowska, M., Lam, V. and Hawthorne, W. J. (2015). Single-port onlay mesh repair of recurrent inguinal hernias after failed anterior and laparoscopic repairs. JSLS : Journal of the Society of Laparoendoscopic Surgeons / Society of Laparoendoscopic Surgeons. 1 (19) , e2014.00212-e2014.00212.

  • Guo, F., Xing, X., Hawthorne, W. J., Dong, Q., Ye, B., Zhang, J., Liang, Q., Nie, W. and Wang, W. (2014). Characterization of PERV in a new conserved pig herd as potential donor animals for xenotransplantation in China. Virology Journal. (11)
  • Hawthorne, W., Salvaris, E., Phillips, P., Hawkes, J., Liuwantara, D., Burns, H., Barlow, H., Stewart, A., Peirce, S., Hu, M., O'Connell, P., et al (2014). Control of IBMIR in Neonatal Porcine Islet Xenotransplantation in Baboons. American Journal of Transplantation. 14 (6) , 1300-1309. [More Information]
  • Jin, X., Wang, Y., Hawthorne, W., Hu, M., Yi, S., O'Connell, P. (2014). Enhanced Suppression of the Xenogeneic T-Cell Response in Vitro by Xenoantigen Stimulated and Expanded Regulatory T Cells. Transplantation. 97 (1) , 30-38. [More Information]

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  • Wong, M. S., Tso, A., Ali, M., Hawthorne, W. J. and Manolios, N. (2014). Novel T-cell inhibiting peptides delay the onset of Type 1 diabetes in non-obese diabetic mice. Diabetes & Metabolism. 3 (40) , 229-234.
  • Tran, H., Turingan, I., Tran, K., Zajkowska, M., Lam, V. and Hawthorne, W. (2014). Potential benefits of single-port compared to multiport laparoscopic inguinal herniorraphy: a prospective randomized controlled study. Hernia. 12 (3) , e29-e29.
  • Brady, J., Harrison, L., Goodman, D., Cowan, P., Hawthorne, W., O'Connell, P., Sutherland, R., Lew, A. (2014). Preclinical screening for acute toxicity of therapeutic monoclonal antibodies in a hu-SCID model. Clinical & Translational Immunology. 3 (12) , 1-7.
  • Stewart, J., Tarantal, A., Hawthorne, W., Salvaris, E., O'Connell, P., Nottle, M., D'Apice, A., Cowan, P., Kearns-Jonker, M. (2014). Rhesus monkeys and baboons develop clotting factor VIII inhibitors in response to porcine endothelial cells or islets. Xenotransplantation. 21 (4) , 341-352. [More Information]
  • Hanh Minh, T., Kim, T., Zajkowska, M., Lam, V. and Hawthorne, W. (2014). Single-Incision Laparoscopic Intraperitoneal Onlay Mesh Repair for the Treatment of Multiple Recurrent Inguinal Hernias. Jsls-Journal of the Society of Laparoendoscopic Surgeons. 3 (35) , 469-+.
  • Chen, Y., Stewart, J., Gunthart, M., Hawthorne, W., Salvaris, E., O'Connell, P., Nottle, M., d'Apice, A., Cowan, P., Kearns-Jonker, M. (2014). Xenoantibody response to porcine islet cell transplantation using GTKO, CD55, CD59, and fucosyltransferase multiple transgenic donors. Xenotransplantation. 21 (3) , 244-253. [More Information]

  • Cantley, J., Walters, S., Jung, M., Weinberg, A., Cowley, M., Whitworth, P., Kaplan, W., Hawthorne, W., O'Connell, P., Weir, G., et al (2013). A Preexistent Hypoxic Gene Signature Predicts Impaired Islet Graft Function and Glucose Homeostasis. Cell Transplantation. 22 (11) , 2147-2159. [More Information]
  • Brady, J., Sutherland, R., Hancock, M., Kitsoulis, S., Lahoud, M., Phillips, P., Hawthorne, W., d'Apice, A., Cowan, P., Harrison, L., O'Connell, P., et al (2013). Anti-CD2 producing pig xenografts effect localized depletion of human T cells in a huSCID model. Xenotransplantation. 20 (2) , 100-109. [More Information]
  • Stokes, R., Cheng, K., Deters, N., Lau, S., Hawthorne, W., O'Connell, P., Stolp, J., Grey, S., Loudovaris, T., Kay, T., Gunton, J., et al (2013). Hypoxia-inducible factor-1α (HIF-1α) potentiates β-cell survival after islet transplantation of human and mouse islets. Cell Transplantation. 22 (2) , 253-266. [More Information]

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  • Hu, M., Wang, C., Zhang, G., Saito, M., Wang, Y., Fernandez, M., Wang, Y., Wu, H., Hawthorne, W., Jones, C., O'Connell, P., Bishop, A., Sharland, A., Alexander, S., et al (2013). Infiltrating Foxp3+ regulatory T cells from spontaneously tolerant kidney allografts demonstrate donor-specific tolerance. American Journal of Transplantation. 13 , 2819-2830. [More Information]
  • O'Connell, P., Holmes-Walker, J., Goodman, D., Hawthorne, W., Loudovaris, T., Gunton, J., Thomas, H., Grey, S., Drogemuller, C., Ward, G., et al (2013). Multicenter Australian Trial of Islet Transplantation: Improving Accessibility and Outcomes. American Journal of Transplantation. 13 (7) , 1850-1858. [More Information]
  • Hu, M., Wu, J., Zhang, G., Wang, Y., Watson, D., Yi, S., Hawthorne, W., O'Connell, P., Alexander, S. (2013). Selective Depletion of Alloreactive T cells Leads to Long-Term Islet Allograft Survival Across a Major Histocompatibility Complex Mismatch in Diabetic Mice. Cell Transplantation. 22 (10) , 1929-1941. [More Information]
  • O'Connell, P., Cowan, P., Hawthorne, W., Yi, S., Lew, A. (2013). Transplantation of Xenogeneic Islets: Are We There Yet?. Current Diabetes Reports. 13 (5) , 687-694. [More Information]

  • Yi, S., Ji, M., Wu, J., Ma, X., Phillips, P., Hawthorne, W., O'Connell, P. (2012). Adoptive Transfer With In Vitro Expanded Human Regulatory T Cells Protects Against Porcine Islet Xenograft Rejection via Interleukin-10 in Humanized Mice. Diabetes. 61 (5) , 1180-1191. [More Information]
  • Campbell, P., Weinberg, A., Chee, J., Mariana, L., Ayala, R., Hawthorne, W., O'Connell, P., Loudovaris, T., Cowley, M., Kay, T., et al (2012). Expression of Pro- and Anti-apoptotic Molecules of the Bcl-2 Family in Human Islets Postisolation. Cell Transplantation. 21 (1) , 49-60. [More Information]
  • Cowley, M., Weinberg, A., Zammit, N., Walters, S., Hawthorne, W., Loudovaris, T., Thomas, H., Kay, T., Gunton, J., Alexander, S., O'Connell, P., et al (2012). Human islets express a marked proinflammatory molecular signature prior to transplantation. Cell Transplantation. 21 (9) , 2063-2078. [More Information]

  • Hawthorne, W., Simond, D., Stokes, R., Patel, A., Walters, S., Burgess, J., O'Connell, P. (2011). Pre-clinical model of composite foetal pig pancreas fragment/renal xenotransplantation to treat renal failure and diabetes. Xenotransplantation. 18 (6) , 390-399. [More Information]
  • Hawthorne, W., Simond, D., Stokes, R., Patel, A., Walters, S., Burgess, J., O'Connell, P. (2011). Subcapsular Fetal Pig Pancreas Fragment Transplantation Provides Normal Blood Glucose Control in a Preclinical Model of Diabetes. Transplantation. 91 (5) , 515-521. [More Information]
  • Ji, M., Yi, S., Smith-Hurst, H., Phillips, P., Wu, J., Hawthorne, W., O'Connell, P. (2011). The Importance of Tissue Factor Expression by Porcine NICC in Triggering IBMIR in the Xenograft Setting. Transplantation. 91 (8) , 841-846. [More Information]

  • Cheng, K., Ho, K., Stokes, R., Scott, C., Lau, S., Hawthorne, W., O'Connell, P., Loudovaris, T., Kay, T., Kulkarni, R., Biankin, A., Kench, J., Gunton, J., et al (2010). Hypoxia-inducible factor-1alpha regulates beta cell function in mouse and human islets. Journal of Clinical Investigation. 120 (6) , 2171-2183. [More Information]

  • Londrigan, S., Brady, J., Sutherland, R., Cowan, P., d'Apice, A., Hawthorne, W., O'Connell, P., Lew, A. (2009). Optimizing transduction of pig islet cell clusters for xenotransplantation.. Xenotransplantation. 16 (1) , 45-46. [More Information]
  • Akima, S., Hawthorne, W., Favaloro, E., Patel, A., Blyth, K., Mudaliar, M., Chapman, J., O'Connell, P. (2009). Tirofiban and Activated Protein C Synergistically Inhibit the Instant Blood Mediated Inflammatory Reaction (IBMIR) from Allogeneic Islet Cells Exposure to Human Blood. American Journal Of Transplantation. 9 , 1533-1540. [More Information]

  • Feller, J., Simpson, A., Nelson, M., O'Connell, P., Swan, M., Hawthorne, W., Tao, C., O'Brien, B. (2008). Growth Promoting Effect of Rh(D) Antibody on Human Pancreatic Islet Cells. Journal of Clinical Endocrinology and Metabolism. 93 (9) , 3560-3567. [More Information]
  • Wu, J., Yi, S., Ouyang, L., Jimenez, E., Simond, D., Wang, W., Wang, Y., Hawthorne, W., O'Connell, P. (2008). In Vitro Expanded Human CD4+CD25+ Regulatory T Cells are Potent Suppressors of T-Cell-Mediated Xenogeneic Responses. Transplantation. 85 (12) , 1841-1848. [More Information]
  • Fu, Y., Yi, S., Wu, J., Jimenez-Vera, E., Simond, D., Hawthorne, W., O'Connell, P. (2008). In vitro suppression of xenoimmune-mediated macrophage activation by human CD4+CD25+ regulatory T cells. Transplantation. 86 (6) , 865-874. [More Information]

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  • Fu, Y., Lu, X., Yi, S., O'Hara, J., Hawthorne, W., Hucker, K., O'Connell, P. (2008). Selective rejection of porcine islet xenografts by macrophages. Xenotransplantation. 15 (5) , 307-312. [More Information]
  • Horton, P., Hawthorne, W., Walters, S., Patel, T., Stewart, G., Allen, R., Chapman, J. (2008). Tolerance Induction in a Large-Animal Model Using Total Lymphoid Irradiation and Intrathymic Bone Marrow. Transplantation. 86 (12) , 1830-1836. [More Information]

  • Chandra, A., Ouyang, L., Yi, S., Wong, J., Ha, H., Walters, S., Patel, A., Stokes, R., Jardine, M., Hawthorne, W., O'Connell, P. (2007). Chemokine and toll-like receptor signaling in macrophage mediated islet xenograft rejection. Xenotransplantation. 14 (1) , 48-59.
  • Londrigan, S., Brady, J., Sutherland, R., Hawthorne, W., Thomas, H., Jhala, G., Cowan, P., Kay, T., O'Connell, P., Lew, A. (2007). Evaluation of promoters for driving efficient transgene expression in neonatal porcine islets. Xenotransplantation. 14 (2) , 119-125.
  • Yi, S., Wang, Y., Chandra, A., O'Hara, J., Wu, J., Ouyang, L., Burgess, J., Hawthorne, W., Wu, H., Chadban, S., O'Connell, P. (2007). Requirement of MyD88 for macrophage-mediated islet xenograft rejection after adoptive transfer. Transplantation. 83 (5) , 615-623.

  • O'Connell, P., Hawthorne, W., Holmes-Walker, D., Nankivell (Nankievell), B., Gunton, J., Patel, A., Walters, S., Pleass, H., Allen, R., Chapman, J. (2006). Clinical islet transplantation in type 1 diabetes mellitus: results of Australia's first trial.. Medical Journal of Australia. 184 (5) , 221-225.
  • Akima, S., Hawthorne, W., Koutts, J., Patel, A., Burgess, J., O'Hara, J., Mudaliar, Y., Favaloro, E., O'Connell, P. (2006). Differences in the efficacy of recombinant human activated protein C against allogeneic and xenogeneic IBMIR. 84 (3) , A16-A16.
  • Hawthorne, W., Patel, A., O'Hara, J., Akima, S., Salvaris, E., Nottle, M., d'Aspice, A., Cowan, P., O'Connell, P. (2006). Elimination of the alpha Gal antigen on NICC reduces ibmir following exposure of pig NICC to human blood. 24th Annual Scientific Meeting of the Transplantation Society of Australia and New Zealand (2006). 84 , A1-A1.

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  • O'Connell, P., Lew, A., Cowan, P., Londrigan, S., Hawthorne, W., Nottle, M., d'Apice, A. (2006). Islet xenotransplantation: progress towards a clinical therapy. Current Opinion in Organ Transplantation. 11 (2) , 174-179.
  • Chandra, A., Wong, J., Yi, S., Ha, H., Patel, A., O'Connell, P., Hawthorne, W. (2006). Lack of IL-15 reduces recruitment of xenoreactive leukocytes into discordant islet xenografts but does not prolong graft survival. 24th Annual Scientific Meeting of the Transplantation Society of Australia and New Zealand (2006). 84 , A8-A9.
  • Simond, D., Moran, C., Garkavenko, O., O'Connell, P., Hawthorne, W. (2006). Real-time PCR detection of porcine endogenous retroviruses. 24th Annual Scientific Meeting of the Transplantation Society of Australia and New Zealand (2006). 84 , A24-A24.
  • Hawthorne, W., Stokes, R., Patel, A., Burgess, J., Walters, S., Simond, D., O'Connell, P. (2006). Westran fetal pig pancreas fragment transplants provide long-term normoglycaemia in adult pi. 24th Annual Scientific Meeting of the Transplantation Society of Australia and New Zealand (2006). 84 , A8-A8.

  • Wong, K., Kable, K., Hawthorne, W., Robertson, P., Chan, K., Nankivell (Nankievell), B., O'Connell, P., Chapman, J., Lau, H., Pleass, H., Allen, R. (2005). A comparison of 2 surgical techniques in pancreas transplantation. Immunology and Cell Biology. 83 (4) , A23-A24.
  • Lee, J., Simond, D., Hawthorne, W., Walters, S., Patel, A., Smith, D., O'Connell, P., Moran, C. (2005). Characterization of the swine major histocompatibility complex alleles at eight loci in Westran pigs. Xenotransplantation. 12 (4) , 303-307.
  • O'Connell, P., Hawthorne, W., Simond, D., Chapman, J., Chen, Y., Patel, A., Walters, S., Burgess, J., Weston, L., Stokes, R., Moran, C., Allen, R. (2005). Genetic and Functional evaluation of the level of inbreeding of the Westran pig: a herd with potential for use in xenotransplantation. Xenotransplantation. 12 (4) , 308-315.

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  • Yi, S., Ouyang, L., Ha, H., O'Hara, J., Chandra, A., Akima, S., Hawthorne, W., Patel, A., Stokes, R., O'Connell, P. (2005). Involvement of CCR5 Signaling in Macrophage Recruitment to Porcine Islet Xenografts. Transplantation. 80 (10) , 1468-1475.
  • Gunton, J., Kulkarni, R., Yim, S., Okada, T., Hawthorne, W., Tseng, Y., Roberson, R., Ricordi, C., O'Connell, P., Gonzalez, F., et al (2005). Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes.. Cell. 122 (3) , 337-349.

  • Yi, S., Hawthorne, W., Lehnert, A., Ha, H., Wong, J., Rooijen, N., Davey, K., Patel, A., Walters, S., Chandra, A., O'Connell, P. (2003). T Cell-Activated Macrophages Are Capable of Both Recognition and Rejection of Pancreatic Islet Xenografts. The Journal of Immunology. 170 (5) , 2750-2758.

  • Lehnert, A., Hawthorne, W., O'Connell, P., Mottram, P., Han, W., Walters, S., Patel, A., Cowan, P., d'Apice, A. (2001). Blockage of the cd28 and cd40 pathways result in the acceptance of pig and rat islet xenografts but not rat cardiac grafts in mice. Transplant Immunology. 9 , 51-56.
  • Allen, R., Nankivell (Nankievell), B., Hawthorne, W., O'Connell, P., Chapman, J. (2001). Pancreas and islet transplantation: an unfinished journey. Transplantation Proceedings. 33 , 3485-3488.

  • Hawthorne, W., Cachia, A., Walters, S., Patel, A., Clarke, J., O'Connell, P., Chapman, J., Allen, R. (2000). A large-animal model to evaluate the clinical potential of fetal pig pancreas fragment transplantation. Cell Transplantation. 9 , 867-875.
  • Horton, P., Hawthorne, W., Walters, S., Patel, A., O'Connell, P., Chapman, J., Allen, R. (2000). Induction of allogenic islet tolerance in a large-animal model. Cell Transplantation. 9 , 877-887.