Liver cancer is Australia’s fastest growing cancer in terms of incidence and mortality. Around the world, it’s the third most common cause of cancer related deaths. The prognosis for liver cancer is dismal and this is largely due to a poor understanding of the cellular and molecular interactions causing its development, progression and resistance to current treatments.
Our basic and translational research focuses on key molecular and cellular interactions which drive liver cancer. The overall goal of our research is to provide new, targeted therapies which will improve overall survival and quality of life in patients suffering from this deadly disease.
We are particularly interested in understanding the role of inflammation and liver cancer stem cells in the development, treatment resistance, metastasis, and relapse of liver cancer. We employ a wide range of novel approaches in our research to solve key questions in liver cancer biology.