Our research finds ways of using genes or genetic material to replace cardiac devices to treat and prevent sudden death from heart rhythm problems.
We aim to understand the molecular basis of cardiac rhythm and conduction, and to uncover new molecular targets and approaches for the treatment of cardiac arrhythmias.
We are using gene therapy in research models to alter the heart to positively affect arrhythmia – to restore conduction following a heart attack in order to prevent sudden death and to turn heart cells into pacemaker cells with the capacity to beat on their own.
Led by practising cardiologists, our work has direct relevance to patients. Our basic laboratory research is combined with clinical research conducted through the Department of Cardiology at Westmead Hospital. We are co-located and closely aligned with the Cardiac Regeneration Laboratory.