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Autoimmunity & Amyloidosis Group

Publications

Lee AYS, Lin MW, Reed JH. Anti-Ro52/TRIM21 serological subsets identify differential clinical and laboratory parameters. Clin Rheumatol. 2022 Jul 23;. doi: 10.1007/s10067-022-06299-5.
 
Langley DB, Schofield P, Nevoltris D, Jackson J, Jackson KJL, Peters TJ, Burk M, Matthews JM, Basten A, Goodnow CC, van Nunen S, Reed JH, Christ D. Genetic and structural basis of the human anti-α-galactosyl antibody response. Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2123212119. doi: 10.1073/pnas.2123212119.
 
Reed JH. Transforming mutations in the development of pathogenic B cell clones and autoantibodies. Immunol Rev. 2022 May;307(1):101-115. doi: 10.1111/imr.13064.
 
Masle-Farquhar E, Peters TJ, Miosge LA, Parish IA, Weigel C, Oakes CC, Reed JH, Goodnow CC. Uncontrolled CD21low age-associated and B1 B cell accumulation caused by failure of an EGR2/3 tolerance checkpoint. Cell Rep. 2022 Jan 18;38(3):110259. doi: 10.1016/j.celrep.2021.110259.
 
Lee AYS, Reed JH, Gordon TP. Anti-Ro60 and anti-Ro52/TRIM21: Two distinct autoantibodies in systemic autoimmune diseases. J Autoimmun. 2021 Nov;124:102724. doi: 10.1016/j.jaut.2021.102724.
 
Zhang Z, Jara CJ, Singh M, Xu H, Goodnow CC, Jackson KJ, Reed JH. Human transitional and IgMlow mature naïve B cells preserve permissive B-cell receptors. Immunol Cell Biol. 2021 Sep;99(8):865-878. doi: 10.1111/imcb.12478
 
Reed JH, Verstappen GM, Rischmueller M, Bryant VL. When B cells break bad: development of pathogenic B cells in Sjögren's syndrome. Clin Exp Rheumatol. 2020 Jul-Aug;38 Suppl 126(4):271-282.
 
Singh M, Jackson KJL, Wang JJ, Schofield P, Field MA, Koppstein D, Peters TJ, Burnett DL, Rizzetto S, Nevoltris D, Masle-Farquhar E, Faulks ML, Russell A, Gokal D, Hanioka A, Horikawa K, Colella AD, Chataway TK, Blackburn J, Mercer TR, Langley DB, Goodall DM, Jefferis R, Gangadharan Komala M, Kelleher AD, Suan D, Rischmueller M, Christ D, Brink R, Luciani F, Gordon TP, Goodnow CC, Reed JH. Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody. Cell. 2020 Mar 5;180(5):878-894.e19. doi: 10.1016/j.cell.2020.01.029.
 
Wang JJ, Reed JH, Colella AD, Russell AJ, Murray-Brown W, Chataway TK, Jackson KJL, Goodnow CC, Gordon TP. Molecular Profiling and Clonal Tracking of Secreted Rheumatoid Factors in Primary Sjögren's Syndrome. Arthritis Rheumatol. 2018 Oct;70(10):1617-1625. doi: 10.1002/art.40539.
 
Schofield P, Vazquez-Lombardi R, Abdelatti M, Nevoltris D, Goodnow CC, Christ D, Reed JH. Sequencing and Affinity Determination of Antigen-Specific B Lymphocytes from Peripheral Blood. Methods Mol Biol. 2018;1827:287-309. doi: 10.1007/978-1-4939-8648-4_15.
 
Reed JH, Gorny MK, Li L, Cardozo T, Buyon JP, Clancy RM. Ro52 autoantibodies arise from self-reactive progenitors in a mother of a child with neonatal lupus. J Autoimmun. 2017 May;79:99-104. doi: 10.1016/j.jaut.2017.01.004.