Publications

  • Onkelen van RS, Gosselink MP, van Meurs M, Melief MJ, Schouten WR, Laman JD.Pro-inflammatory cytokines in cryptoglandular anal fistulas. Tech Coloproctol. 2016 ;20(9):619-25.
  • Gosselink MP, van Onkelen RS, Schouten WR. The cryptoglandular theory revisited. Colorectal Dis. 2015;17(12):1041-3.
  • Onkelen van RS, Gosselink MP, Laman JD, Schouten WR. Inflammation in anal fistula. Colorectal Dis. 2015;17(7):643-4.
  • Scott F, Seghal A, Joshi HM, Yeung TM, Gosselink MP. Quality of patient information on the internet for the treatment of anal fistula and anal fissure.Tech Coloproctol. 2014;18:1181-3.
  • Van Onkelen RS, Gosselink MP, Thijsse S, Schouten WR. Predictors of outcome after transanal advancement flap repair for high transsphincteric fistulas. Accepted for Dis Colon Rectum. 2014; 57:1007-11.
  • Van Onkelen RS, Gosselink MP, van Rosmalen J, Thijsse S, Schouten WR. Different characteristics of high and low transsphincteric fistulae. Colorectal Dis. 2014; 16:471-5.
  • Schouten WR, Gosselink MP, Thijsse S, van Onkelen R. Intersphincteric ligation of perianal fistula. Ned Tijdschr Geneeskd. 2013;157:A6505.
  • Van Onkelen RS, Gosselink MP, Schouten WR. Treatment of anal fistulas with high intersphincteric extension. Dis Colon Rectum. 2013;56:987-91.
  • Van Onkelen RS, Mitalas LE, Gosselink MP, van Belkum A, Laman JD, Schouten WR. Assessment of microbiota and peptidoglycan in perianal fistulas. Diagn Microbiol Infect Dis. 2013;75:50-4.
  • Van Onkelen RS, Gosselink MP, Schouten WR. Ligation of the intersphincteric fistula tract in low transsphincteric fistulae: a new technique to avoid fistulotomy. Colorectal Dis. 2013;15:587-91.
  • Mitalas LE, van Onkelen RS, Monkhorst K, Zimmerman DDE, Gosselink MP, Schouten WR. Identification of epithelialization in high transsphincteric fistulas. Tech Coloproctol. 2012.
  • Mitalas LE, van Onkelen RS, Gosselink MP, Zimmerman DDE, Schouten WR. The anal fistula plug as an adjunct to transanal advancement flap repair. Dis Colon Rectum. 2010;53:1713.
  • Mitalas LE, van Wijk JJ, Gosselink MP, Doornebosch PE, Zimmerman DDE, Schouten WR. Seton drainage prior to transanal advancement flap repair: useful or not? Int J Colorectal Dis. 2010;25:1499-502.
  • Mitalas LE, Schouten SB, Gosselink MP, Oom DM, Zimmerman DDE, Schouten WR. Does rectal mucosal blood flow affect the outcome of transanal advancement flap repair? Dis Colon Rectum. 2009;52:1395-9.
  • Mitalas LE, Gosselink MP, Oom DM, Zimmerman DDE, Schouten WR. Adverse effect of BioGlue on the outcome of transanal advancement flap repair. Dis Colon Rectum. 2009;52:754.
  • Mitalas LE, Gosselink MP, Oom DM, Zimmerman DDE, Schouten WR. Required length of follow-up after transanal advancement flap repair of high transsphincteric fistulas. Colorectal Dis. 2009;11:726-8.
  • Mitalas LE, Gosselink MP, Oom DM, Zimmerman DDE, Schouten WR. Obliteration of the fistulous tract with BioGlue adversely affects the outcome of transanal advancement flap repair. Tech Coloproctol. 2008;12:225-8.
  • Mitalas LE, Gosselink MP, Zimmerman DD, Schouten WR. Repeat transanal advancement flap repair: impact on the overall healing rate of high transsphincteric fistulas and on fecal continence. Dis Colon Rectum. 2007;50:1508-11.
  • Oom DM, Gosselink MP, Van Dijl VR, Zimmerman DDE, Schouten WR. Puborectal sling interposition for the treatment of rectovaginal fistulas. Tech Coloproctol. 2006 ; 10:125-30.
  • Schouten WR, Gosselink MP. Long-term outcome following loose-seton technique for external sphincter preservation in complex anal fistula. Tech Coloproct. 2005; 9: 79.
  • Zimmerman DDE, Gosselink MP, Mitalas LE, Delemarre JBV, Hop WC, Briel JW, Schouten WR. Smoking impairs rectal mucosal bloodflow - a Pilot study. Possible implications for transanal flap repair. Dis Colon Rect. 2005; 48: 1228-32.
  • Zimmerman DDE, Gosselink MP, Hop WC, Darby M, Briel JW, Schouten WR. Impact of two different types of anal retractor on fecal continence after fistula repair: a prospective, randomized, clinical trial. Dis Colon Rectum. 2003; 46:1674-9.
  • Zimmerman DDE, Delemarre JB, Gosselink MP, Hop WC, Briel JW, Schouten WR. Smoking affects the outcome of transanal mucosal advancement flap repair of trans-sphincteric fistulas. Br J Surg. 2003; 90: 351-4.
  • Zimmerman DDE, Gosselink MP, Briel JW, Schouten WR.The outcome of transanal advancement flap repair of rectovaginal fistulas is not improved by an additional labial fat flap transposition. Tech Col Proct. 2002; 6: 37-42.
  • Zimmerman DDE, Briel JW, Gosselink MP, Schouten WR. Anocutaneous advancement flap repair of transsphincteric fistulas. Dis Colon Rectum. 2001; 44: 1474-80.
Expand all
  • Cunningham, A., Harman, A., Donaghy, H. (2007). DC-SIGN 'AIDS' HIV immune evasion and infection. Nature Immunology. 8 (6) , 556-558.

  • Watson, S., Mercier, S., Bye, C., Wilkinson, J., Cunningham, A., Harman, A. (2007). Determination of suitable housekeeping genes for normalisation of quantitative real time PCR analysis of cells infected with human immunodeficiency virus and herpes viruses. Virology Journal. 4 (130) , 1-5.

  • Wightman, F., Hao, K., Solomon, A., Saleh, S., Harman, A., Cunningham, A., Gray, L., Churchill, M., Cameron, P., Dear, A., et al (2013). Entinostat is a histone deacetylase inhibitor selective for class 1 histone deacetylases and activates HIV production from latently infected primary T cells. AIDS. 27 (18) , 2853-2862.

  • Cameron, P., Saleh, S., Sallmann, G., Solomon, A., Wightman, F., Evans, V., Boucher, G., Haddad, E., Sekaly, R., Harman, A., Cunningham, A., et al (2010). Establishment of HIV-1 Latency in Resting CD4+ T Cells Depends on Chemokine-Induced Changes in the Actin Cytoskeleton. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 107 (39) , 16934-16939.

  • Marsden, V., Donaghy, H., Bertram, K., Harman, A., Nasr, N., Keoshkerian, E., Merten, S., Lloyd, A., Cunningham, A. (2015). Herpes Simplex Virus Type 2-Infected Dendritic Cells Produce TNF-a, Which Enhances CCR5 Expression and Stimulates HIV Production from Adjacent Infected Cells. Journal of Immunology. 194 (9) , 4438-4445.

  • Marsden, V., Donaghy, H., Bertram, K., Harman, A., Nasr, N., Keoshkerian, E., Merten, S., Lloyd, A., Cunningham, A. (2015). Herpes Simplex Virus Type 2-Infected Dendritic Cells Produce TNF-a, Which Enhances CCR5 Expression and Stimulates HIV Production from Adjacent Infected Cells. Journal of Immunology. 194 (9) , 4438-4445.

  • Marsden, V., Donaghy, H., Bertram, K., Harman, A., Nasr, N., Keoshkerian, E., Merten, S., Lloyd, A., Cunningham, A. (2015). Herpes Simplex Virus Type 2–Infected Dendritic Cells Produce TNF-a, Which Enhances CCR5 Expression and Stimulates HIV Production from Adjacent Infected Cells. The Journal of Immunology. 194 (9) , 4438-4445.

  • Harman, A., Nasr, N., Feetham, A., Galoyan, A., Alshehri,, A., Rambukwelle, D., Botting, R., Hiener, B., Diefenbach, E., Diefenbach, R., Kim, M., Cunningham, A., et al (2015). HIV blocks interferon induction in human dendritic cells and macrophages by dysregulation of TBK1. Journal of Virology. 89 (13) , 6575-6584.

  • Harman, A., Wilkinson, J., Bye, C., Bosnjak, L., Stern, J., Nicholle, M., Lai, J., Cunningham, A. (2006). HIV Induces Maturation of Monocyte-Derived Dendritic Cells and Langerhans Cells.. The Journal of Immunology. 177 (10) , 7103-7113.

  • Nasr, N., Harman, A., Turville, S., Cunningham, A. (2014). HIV infection of dendritic cells. Human Retroviruses: Method and Protocols. 1087 , 221-232.

  • Harman, A., Lai, J., Turville, S., Samarajiwa, S., Gray, L., Marsden, V., Mercier, S., Jones, K., Nasr, N., Rustagi, A., Cunningham, A., et al (2011). HIV infection of dendritic cells subverts the interferon induction pathway via IRF1 and inhibits type 1 interferon production. Blood. 118 (2) , 298-308.

  • Saleh, S., Lu, H., Evans, V., Harrison, D., Zhou, J., Jaworowski, A., Sallmann, G., Cheong, K., Mota, T., Harman, A., Cunningham, A., et al (2016). HIV integration and the establishment of latency in CCL19-treated resting CD4(+) T cells require activation of NF-[subscript K]B. Retrovirology. 13 (1) , 1-12.

  • Nasr, N., Maddocks, S., Turville, S., Harman, A., Woolger, N., Helbig, K., Wilkinson, J., Bye, C., Wright, T., Rambukwelle, D., Donaghy, H., Cunningham, A., et al (2012). HIV-1 infection of human macrophages directly induces viperin which inhibits viral production. Blood. 120 (4) , 778-788.

  • Harman, A., Kraus, M., Bye, C., Byth Wilson, K., Turville, S., Tang, O., Mercier, S., Nasr, N., Stern, J., Slobedman, B., Cunningham, A., et al (2009). HIV-1-infected dendritic cells show 2 phases of gene expression changes, with lysosomal enzyme activity decreased during the second phase. Blood. 114 (1) , 85-94.

  • Harman, A., Bye, C., Nasr, N., Sandgren, K., Kim, M., Mercier, S., Botting, R., Lewin, S., Cunningham, A., Cameron, P. (2013). Identification of Lineage Relationships and Novel Markers of Blood and Skin Human Dendritic Cells. The Journal of Immunology. 190 (1) , 66-79.

  • Cunningham, A., Harman, A., Kim, M., Nasr, N., Lai, J. (2013). Immunobiology of Dendritic Cells and the Influence of HIV Infection. HIV Interactions with Dendritic Cells: Infection and Immunity. , 1-44.

  • Nasr, N., Lai, J., Botting, R., Mercier, S., Harman, A., Kim, M., Turville, S., Center, R., Domagala, T., Gorry, P., Cunningham, A., et al (2014). Inhibition of Two Temporal Phases of HIV-1 Transfer from Primary Langerhans Cells to T Cells: The Role of Langerin. The Journal of Immunology. 193 (5) , 2554-2564.

  • Cunningham, A., Harman, A., Nasr, N. (2013). Initial HIV mucosal infection and dendritic cells. EMBO Molecular Medicine. 5 (5) , 658-660.

  • Botting, R., Rana, H., Bertram, K., Rhodes, J., Barhalou, H., Nasr, N., Cunningham, A., Harman, A. (2017). Langerhans cells and sexual transmission of HIV and HSV. Reviews in Medical Virology. 27 (2) , e1923.

  • Cunningham, A., Donaghy, H., Harman, A., Turville, S. (2010). Manipulation of dendritic cell function by viruses.. Current Opinion in Microbiology. 13 (4) , 524-9.

  • Nasr, N., Alshehri, A., Wright, T., Shahid, M., Heiner, B., Harman, A., Botting, R., Helbig, K., Beard, M., Suzuki, K., Cunningham, A., et al (2017). Mechanism of interferon-stimulated gene induction in HIV-1- infected macrophages. Journal of Virology. 91 (20)

  • Nasr, N., Alshehri, A., Wright, T., Shahid, M., Heiner, B., Harman, A., Botting, R., Helbig, K., Beard, M., Suzuki, K., Cunningham, A., et al (2017). Mechanism of interferon-stimulated gene induction in HIV-1- infected macrophages. Journal of Virology. 91 (20)

  • Clark, G., Kupresanin, F., Fromm, P., Ju, X., Muusers, L., Silveira, P., Elgundi, Z., Gasiorowski, R., Papadimitrious, M., Bryant, C., Lee, K., Harman, A., Hart, D., et al (2016). New insights into the phenotype of human dendritic cell populations. Clinical & Translational Immunology. 5 (1) , 1-12.

  • Lai, J., Bernhard, O., Turville, S., Harman, A., Wilkinson, J. (2009). Oligomerization of the macrophage mannose receptor enhances gp120-mediated binding of HIV-1. Journal of Biological Chemistry. 284 (17) , 11027-11038.

  • Botting, R., Bertram, K., Baharlou, H., Sandgren, K., Fletcher, J., Rhodes, J., Rana, H., Plasto, T., Wang, X., Lim, J., Cunningham, A., Harman, A., et al (2017). Phenotypic and functional consequences of different isolation protocols on skin mononuclear phagocytes. Journal of Leukocyte Biology. 101 (6) , 1393-1403.

  • Botting, R., Bertram, K., Baharlou, H., Sandgren, K., Fletcher, J., Rhodes, J., Rana, H., Plasto, T., Wang, X., Lim, J., Cunningham, A., Harman, A., et al (2017). Phenotypic and functional consequences of different isolation protocols on skin mononuclear phagocytes. Journal of Leukocyte Biology. 101 (6) , 1393-1403.

  • Kim, M., Truong, N., James, V., Bosnjak, L., Sandgren, K., Harman, A., Nasr, N., Bertram, K., Olbourne, N., Sawleshwarkar, S., Cunningham, A., et al (2015). Relay of herpes simplex virus between Langerhans cells and dermal dendritic cells in human skin. PLoS Pathogens. 11 (4) , 1-19.

  • Donaghy, H., Bosnjak, L., Harman, A., Marsden, V., Tyring, S., Meng, T., Cunningham, A. (2009). Role for Plasmacytoid Dendritic Cells in the Immune Control of Recurrent Human Herpes Simplex Virus Infection. Journal of Virology. 83 (4) , 1952-1961.

  • Mercier, S., Donaghy, H., Botting, R., Turville, S., Harman, A., Nasr, N., Ji, H., Kusebauch, U., Mendoza, L., Shteynberg, D., Cunningham, A., et al (2013). The Microvesicle Component of HIV-1 Inocula Modulates Dendritic Cell Infection and Maturation and Enhances Adhesion to and Activation of T Lymphocytes. PLoS Pathogens. 9 (10) , 1-18.

  • Harman, A., Kim, M., Nasr, N., Sandgren, K., Cameron, P. (2013). Tissue dendritic cells as portals for HIV entry. Reviews in Medical Virology. 23 (5) , 319-333.