Autoimmune diseases affect millions worldwide, frequently causing chronic illnesses that are difficult to treat. People vary greatly in their susceptibility to these diseases due to genetic risk factors.

Our research seeks to understand how this genetic variation between individuals contributes to disease risk and how people respond to therapies.

Our aim is to find tools to personalise therapy, and to develop new therapeutic approaches to treat autoimmune and other diseases. 

Research Directions

Our main focus is the autoimmune disease multiple sclerosis, especially through finding the basis for interaction between genetic risk factors, drugs, and the environmental risk factors of vitamin D, UV light and the Epstein Barr virus. 

We also work with collaborators on HIV, liver diseases, influenza and amyloidosis.