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Donate now
  • Facebook
  • YouTube
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  • Twitter
  • LinkedIn
  • Contact and Newsletter Sign up
  • Intranet
  • News and Events
  • About
    • WIMR brings together some of the brightest minds to deliver real and significant research breakthroughs for many of the most serious illnesses, improving health and saving lives in Australia and around the world, because people’s lives matter.
      • Acknowledgement of Country
      • Our Story
        • Overview
        • History
        • What we do
        • Facilities
      • Affiliates
      • Governance
      • Research Centres
      • Leadership
      • Contact Us
  • Research
    • WIMR is home to more than 45 research groups concerned with a wide range of human diseases and conditions. Key to our success is the way we connect researchers, clinicians and supporters.
      • Research Centres
      • Research Divisions
        • Liver & Metabolic
        • Cancer
        • Neuroscience & Vision
        • Infection & Immunity
        • Cardio-respiratory
      • Featured Projects
        • INOVATe
      • Core Technologies
        • Cell Imaging
        • Flow Cytometry
        • Genomics
        • Biobanks
      • Can It Be Cured?
  • People
  • Careers
    • Excellent scientific results require exceptional people.
      • Current Opportunities
      • Workplace Benefits
      • Facilities
  • Students
    • Students are a fundamental part of research activity at The Westmead Institute. We give our students the opportunity to do important work that is closely linked to the needs of patients.
      • Meet some of our Students
      • How to Apply
      • Current Student Opportunities
      • Student Scholarships and Grants
      • Why Study at the Westmead Institute?
  • Outcomes
    • The needs of patients are central to everything we do at WIMR. Our research is highly translational. We are passionate about putting our findings into practice and giving hope to those who need it most.
      • Our Discoveries
      • Case Studies
  • Support Us
    • We save lives. You can too. While medical research receives support from governments, some worthwhile projects miss out on receiving grants. Your generosity can help us bridge this gap and translate laboratory discoveries into clinical practice where they can give new hope.
      • Donate to research
        • Make a major gift
        • Make a gift in your will
        • Make a gift in memory
        • Fundraise for WIMR
        • Become a corporate partner
      • Make a regular donation
      • Community Engagement
      • Supporters
      • WIMR Foundation
  1.  Home
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  4. Liver & Metabolic

Liver & Metabolic

Adipose Tissue & Obesity Group

Our research is tackling the epidemic from a new angle by investigating the potential of different types of fat tissue (‘adipose tissue’) to protect patients from the serious metabolic consequences of obesity such as insulin resistance and adult-onset diabetes.

Obesity-related Liver Disease & Cancer Group

We are working on a world-first approach to combat cancer through exploiting the molecular changes that occur in the liver due to obesity.

 

Viral Hepatitis Pathogenesis Group

Our research aims to understand the biological mechanisms underlying viral hepatitis so that we can develop new therapies to cure the infection and reduce its complications.

 

Beta-cell Biology Group

We are studying islet transplantation, which is a potential cure for type 1 diabetes, as well as beta-cell survival and beta-cell function.

 

Vitamin D and Liver Group

Vitamin D deficiency is becoming more common, even in Australia, with people spending less time outdoors and being more careful to avoid excess sun exposure. It is clear that people with liver diseases are more likely to be vitamin D deficient. More importantly, we think that vitamin D deficiency makes many liver diseases progress faster and increases liver-cell damage with insults to the liver.

Liver Cancer Group

Our basic and translational research focuses on key molecular and cellular interactions which drive liver cancer. The overall goal of our research is to provide new, targeted therapies which will improve overall survival and quality of life in patients suffering from this deadly disease.

 
 

Liver Immunology Group

Our research is leading to better understanding of the role of a patient’s genetics and immune response in the development of chronic liver inflammation, fibrosis and ultimately cirrhosis in people with viral and non-viral liver disease.

Functional Genomics Group

Our basic and clinical research focuses on the genetics and epigenetics of liver disease progression and their potential diagnostic and therapeutic translational impacts.

 
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WIMR acknowledges the Darug people who are the traditional custodians of the lands and waterways in Westmead. We pay our respects to Elders past, present and emerging.

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