The pancreatic beta-cells are the only cells in the body which can release insulin, the hormone which controls blood glucose levels.

We study pancreatic beta-cells and islets, the islands of cells in the pancreas where the beta-cells live.

We are studying islet transplantation, which is a potential cure for type 1 diabetes, as well as beta-cell survival and beta-cell function.

We are particularly focussed on ARNT and HIF-1a and their roles in beta-cell function.