• Brain Connectivity Imaging Markers to Confirm Diagnosis for Bipolar vs. Unipolar Depression – A Connectome Approach.


  • Biomarkers to differentiate bipolar from unipolar depression 

Bipolar disorder is the sixth leading cause of disability in Australia and is ranked in the top ten most debilitating of all illnesses worldwide. Differentiating bipolar disorder from unipolar depressive disorders is a major clinical challenge, and optimal clinical care is often hindered by misdiagnosis of this illness. This highlights the need for objective markers that can distinguish both these disorders.

The aim of this study is to identify brain, genetic and cognitive markers (or combinations of markers) for both these disorders.

Participate in our research:

We are seeking individuals aged 18 to 65 to participate in our study. Participation involves visiting The Westmead Institute for Medical Research for an interview, MRI brain scan, cognitive assessments and an EEG.

Individuals with no diagnosable mental illnesses, individuals with bipolar I disorder, and individuals with major depressive disorder are able to apply*. 

If you are interested in participating, or would like further information, contact Wendy Chen on 8627 3306 or The study will be conducted at the Westmead Institute for Medical Research in Sydney, Australia.

* Please note that certian exclusion criteria may prevent you from participating in the study.